Retrograde axonal transport of neurotensin in rat nigrostriatal dopaminergic neurons: Modulation during ageing and possible physiological role

Biochemical and anatomical data are reported which demonstrate for the first time the existence of a retrograde axonal transport process for a neuropeptide, neurotensin, in rat brain. Neurotensin receptors are mainly located in the striatum on nerve terminals of the nigrostriatal dopaminergic pathwa...

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Veröffentlicht in:	Biochemical pharmacology 1994-01, Vol.47 (1), p.53-62
Hauptverfasser:	Castel, Marie-Noëlle, Beaudet, Alain, Laduron, Pierre M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Aging Animals Axons - metabolism Biological Transport Corpus Striatum - metabolism Dopamine - metabolism Male Neurons - metabolism Neurotensin - administration & dosage Neurotensin - metabolism Rats Rats, Sprague-Dawley Receptors, Neurotensin - metabolism Tyrosine 3-Monooxygenase - metabolism
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