Glomus tumor of the cheek: An immunohistochemical demonstration of actin and myosin
A rare case of a buccal glomus tumor was examined by light and electron microscopy. Histologically, the tumor consisted of various vascular spaces surrounded by masses of epithelioid glomus cells, coexisting with a hemangiomatous proliferation of the vessels. Immunohistochemical stainings revealed t...
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Veröffentlicht in: | Oral surgery, oral medicine, oral pathology oral medicine, oral pathology, 1985-07, Vol.60 (1), p.65-71 |
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creator | Saku, Takashi Okabe, Haruo Matsutani, Kazuhiko Sasaki, Motomasa |
description | A rare case of a buccal glomus tumor was examined by light and electron microscopy. Histologically, the tumor consisted of various vascular spaces surrounded by masses of epithelioid glomus cells, coexisting with a hemangiomatous proliferation of the vessels. Immunohistochemical stainings revealed that the tumor cells were positive for smooth-muscle actin and myosin, with various intensities of the stainings. The electron microscope invariably showed microfilaments in the tumor cells. The results suggest that the glomus tumor cells have characteristics of the smooth-muscle cell and the tumor has a hamartomatous nature. |
doi_str_mv | 10.1016/0030-4220(85)90218-X |
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Histologically, the tumor consisted of various vascular spaces surrounded by masses of epithelioid glomus cells, coexisting with a hemangiomatous proliferation of the vessels. Immunohistochemical stainings revealed that the tumor cells were positive for smooth-muscle actin and myosin, with various intensities of the stainings. The electron microscope invariably showed microfilaments in the tumor cells. The results suggest that the glomus tumor cells have characteristics of the smooth-muscle cell and the tumor has a hamartomatous nature.</description><identifier>ISSN: 0030-4220</identifier><identifier>EISSN: 1878-2175</identifier><identifier>DOI: 10.1016/0030-4220(85)90218-X</identifier><identifier>PMID: 2993976</identifier><identifier>CODEN: OSOMAE</identifier><language>eng</language><publisher>Saint Louis, MO: Elsevier Inc</publisher><subject>Actins - metabolism ; Biological and medical sciences ; Cheek ; Dentistry ; Dermatology ; Facial Neoplasms - metabolism ; Facial Neoplasms - pathology ; Facial Neoplasms - ultrastructure ; Glomus Tumor - metabolism ; Glomus Tumor - pathology ; Glomus Tumor - ultrastructure ; Humans ; Male ; Medical sciences ; Middle Aged ; Muscle, Smooth - metabolism ; Muscle, Smooth - pathology ; Muscle, Smooth - ultrastructure ; Myosins - metabolism ; Tumors of the skin and soft tissue. 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Histologically, the tumor consisted of various vascular spaces surrounded by masses of epithelioid glomus cells, coexisting with a hemangiomatous proliferation of the vessels. Immunohistochemical stainings revealed that the tumor cells were positive for smooth-muscle actin and myosin, with various intensities of the stainings. The electron microscope invariably showed microfilaments in the tumor cells. The results suggest that the glomus tumor cells have characteristics of the smooth-muscle cell and the tumor has a hamartomatous nature.</description><subject>Actins - metabolism</subject><subject>Biological and medical sciences</subject><subject>Cheek</subject><subject>Dentistry</subject><subject>Dermatology</subject><subject>Facial Neoplasms - metabolism</subject><subject>Facial Neoplasms - pathology</subject><subject>Facial Neoplasms - ultrastructure</subject><subject>Glomus Tumor - metabolism</subject><subject>Glomus Tumor - pathology</subject><subject>Glomus Tumor - ultrastructure</subject><subject>Humans</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Muscle, Smooth - metabolism</subject><subject>Muscle, Smooth - pathology</subject><subject>Muscle, Smooth - ultrastructure</subject><subject>Myosins - metabolism</subject><subject>Tumors of the skin and soft tissue. 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Premalignant lesions</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Saku, Takashi</creatorcontrib><creatorcontrib>Okabe, Haruo</creatorcontrib><creatorcontrib>Matsutani, Kazuhiko</creatorcontrib><creatorcontrib>Sasaki, Motomasa</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Oral surgery, oral medicine, oral pathology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Saku, Takashi</au><au>Okabe, Haruo</au><au>Matsutani, Kazuhiko</au><au>Sasaki, Motomasa</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Glomus tumor of the cheek: An immunohistochemical demonstration of actin and myosin</atitle><jtitle>Oral surgery, oral medicine, oral pathology</jtitle><addtitle>Oral Surg Oral Med Oral Pathol</addtitle><date>1985-07</date><risdate>1985</risdate><volume>60</volume><issue>1</issue><spage>65</spage><epage>71</epage><pages>65-71</pages><issn>0030-4220</issn><eissn>1878-2175</eissn><coden>OSOMAE</coden><abstract>A rare case of a buccal glomus tumor was examined by light and electron microscopy. Histologically, the tumor consisted of various vascular spaces surrounded by masses of epithelioid glomus cells, coexisting with a hemangiomatous proliferation of the vessels. Immunohistochemical stainings revealed that the tumor cells were positive for smooth-muscle actin and myosin, with various intensities of the stainings. The electron microscope invariably showed microfilaments in the tumor cells. The results suggest that the glomus tumor cells have characteristics of the smooth-muscle cell and the tumor has a hamartomatous nature.</abstract><cop>Saint Louis, MO</cop><pub>Elsevier Inc</pub><pmid>2993976</pmid><doi>10.1016/0030-4220(85)90218-X</doi><tpages>7</tpages></addata></record> |
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subjects | Actins - metabolism Biological and medical sciences Cheek Dentistry Dermatology Facial Neoplasms - metabolism Facial Neoplasms - pathology Facial Neoplasms - ultrastructure Glomus Tumor - metabolism Glomus Tumor - pathology Glomus Tumor - ultrastructure Humans Male Medical sciences Middle Aged Muscle, Smooth - metabolism Muscle, Smooth - pathology Muscle, Smooth - ultrastructure Myosins - metabolism Tumors of the skin and soft tissue. Premalignant lesions |
title | Glomus tumor of the cheek: An immunohistochemical demonstration of actin and myosin |
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