Phosphorylation of the Ras nucleotide exchange factor Son of sevenless by mitogen activated protein kinase

Son of sevenless-1 and -2 (Sos-1 and -2) are guanosine nucleotide exchange factors implicated in the activation of Ras by both the insulin and epidermal growth factor signal transduction pathways. Ras appears to function by initiating the activation of cellular protein kinases including mitogen-acti...

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Veröffentlicht in:	The Journal of biological chemistry 1994-02, Vol.269 (7), p.4717-4720
Hauptverfasser:	CHERNIACK, A. D, KLARLUND, J. K, CZECH, M. P
Format:	Artikel
Sprache:	eng
Schlagworte:	actividad enzimatica activite enzymatique Adenosine Triphosphate - metabolism Animals Base Sequence binding proteins Biological and medical sciences Calcium-Calmodulin-Dependent Protein Kinases - isolation & purification Calcium-Calmodulin-Dependent Protein Kinases - metabolism Cell Line Cell physiology Diptera DNA Primers Drosophila drosophila melanogaster Drosophila melanogaster - metabolism Drosophilidae enzymic activity fosforilacion Fundamental and applied biological sciences. Psychology Guanine Nucleotide Exchange Factors Hemagglutinin Glycoproteins, Influenza Virus Hemagglutinins, Viral - biosynthesis Insect Hormones - metabolism Membrane Proteins - biosynthesis Membrane Proteins - metabolism Molecular and cellular biology Molecular Sequence Data nucleotide nucleotides nucleotidos Peptide Fragments - analysis Phosphorylation Polymerase Chain Reaction protein kinase proteina quinasa proteinas aglutinantes proteine de liaison proteine kinase Proteins - metabolism ras Guanine Nucleotide Exchange Factors Recombinant Fusion Proteins - biosynthesis Signal transduction Son of Sevenless Proteins Substrate Specificity Transfection
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