B cells process and present lupus autoantigens that initiate autoimmune T cell responses

Antibodies against U small nuclear ribonucleoprotein (snRNP) particles are a common finding in the sera of humans with SLE and in certain strains of mice with murine lupus. It is likely that Th cells are important in amplifying this autoantibody response. The focus of this work was to investigate ev...

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Veröffentlicht in:	The Journal of immunology (1950) 1994-02, Vol.152 (3), p.1453-1461
Hauptverfasser:	Mamula, MJ, Fatenejad, S, Craft, J
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antigen-Presenting Cells - immunology Autoantigens - immunology B-Lymphocytes - immunology Biological and medical sciences Experimental and animal immunopathology. Animal models Humans Immune Tolerance Immunization, Passive Immunopathology Lupus Erythematosus, Systemic - immunology Medical sciences Mice Ribonucleoprotein, U1 Small Nuclear - immunology T-Lymphocytes - immunology
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