Anti-β-receptor antibodies in familial cardiomyopathy: Correlation with HLA-DR and HLA-DQ gene polymorphisms

The presence of β-receptor autoantibodies and their relationship to restriction fragment length polymorphisms of the human leukocyte antigen (HLA) class II genes were studied in 42 affected and unaffected members of a family with a heritable disorder of the conduction system and cardiac muscle. Anti...

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Veröffentlicht in:	The American heart journal 1994-02, Vol.127 (2), p.382-386
Hauptverfasser:	Limas, Catherine, Limas, Constantinos J., Boudoulas, Harisios, Bair, Robert, Graber, Harry, Sparks, Libby, Wooley, Charles F.
Format:	Artikel
Sprache:	eng
Schlagworte:	Antibodies Antigens Arrhythmias, Cardiac - genetics Arrhythmias, Cardiac - immunology Autoantibodies Autoantibodies - genetics Biological and medical sciences Biomarkers Cardiac muscle Cardiology. Vascular system Cardiomegaly - genetics Cardiomegaly - immunology Cardiomyopathy Cardiomyopathy, Dilated - genetics Cardiomyopathy, Dilated - immunology Disease Susceptibility - immunology Female Gene polymorphism Genes Genes, MHC Class II - genetics Genetic Predisposition to Disease Heart Heart Block - genetics Heart Block - immunology Heart Failure - genetics Heart Failure - immunology Histocompatibility antigen HLA HLA-DQ Antigens - genetics HLA-DR Antigens - genetics HLA-DR4 Antigen - genetics Humans Leukocytes Male Medical sciences Muscles Myocarditis. Cardiomyopathies Pathogenesis Phenotype Polymorphism, Genetic - genetics Polymorphism, Restriction Fragment Length Receptors Receptors, Adrenergic, beta - genetics Receptors, Adrenergic, beta - immunology
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