Murine epidermal Langerhans cells and splenic dendritic cells present tumor‐associated antigens to primed T cells

We examined the ability of epidermal Langerhans cells and splenic dendritic cells to present tumor‐associated antigens (Ag) to immune T cells. Methylcholanthrene (MCA)‐induced subcutaneous fibrosarcomas derived from C57BL/6 mice were used as tumor models. Our data demonstrate that both murine Langer...

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Veröffentlicht in:	European journal of immunology 1994-02, Vol.24 (2), p.315-319
Hauptverfasser:	Cohen, Philip J., Cohen, Peter A., Rosenberg, Steven A., Mulé, James J., Katz, Stephen I.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antigen-antibody reactions, antigen-antibody complexes, antibody-complement and others. Study of affinity. Antigen presentation Antigen-Presenting Cells - immunology Antigens, Neoplasm - immunology Biological and medical sciences CD4-Positive T-Lymphocytes - immunology Dendritic cells Dendritic Cells - immunology Epidermis - immunology Female Fundamental and applied biological sciences. Psychology Fundamental immunology Immunologic Memory Langerhans cells Langerhans Cells - immunology Lymphocyte Activation Mice Mice, Inbred C57BL Molecular immunology Neoplasms, Experimental - immunology Spleen - immunology Tumor immunity Tumor‐associated antigens
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