13C NMR analysis of intercompartmental flow of one-carbon units into choline and purines in Saccharomyces cerevisiae

In Saccharomyces cerevisiae, the three-carbon of serine is normally the major one-carbon donor, although glycine and formate can substitute for serine. The second carbon of glycine enters via the glycine cleavage system in the mitochondria and can satisfy all cellular one-carbon requirements. It rem...

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Veröffentlicht in:	Biochemistry (Easton) 1994-01, Vol.33 (1), p.74-82
Hauptverfasser:	Pasternack, L.B, Laude, D.A. Jr, Appling, D.R
Format:	Artikel
Sprache:	eng
Schlagworte:	ACIDE AMINE Adenine - metabolism AMINOACIDOS Biological and medical sciences BIOSINTESIS BIOSYNTHESE Carbon Isotopes CARBONE CARBONO CHOLINE Choline - metabolism COLINA ESPECTROSCOPIA RMN Formates - metabolism Fundamental and applied biological sciences. Psychology Genotype GLICINA GLYCINE (ACIDE AMINE) Glycine - metabolism Growth, nutrition, metabolism, transports, enzymes. Molecular biology Guanine - metabolism ISOTOPE RADIOACTIF Magnetic Resonance Spectroscopy - methods METABOLISME METABOLISMO Microbiology MITOCHONDRIE MITOCONDRIA Models, Biological Mycology PURINAS PURINE Purines - metabolism RADIOISOTOPOS SACCHAROMYCES CEREVISIAE Saccharomyces cerevisiae - genetics Saccharomyces cerevisiae - metabolism Serine - metabolism SPECTROSCOPIE RMN TECHNIQUE DES TRACEURS TECNICAS DE TRAZADORES
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