HLA supratypes in an Italian population
A supratype analysis of a North Italian population was performed, using 16 polymorphisms in the HLA region spanning the HLA-A-DP segment. Fourteen supratypes were identified, mostly corresponding to those found in other Caucasoid populations. The degree of their conservation both within the B-DR/DQ...
Gespeichert in:
| Veröffentlicht in: | Immunogenetics (New York) 1994, Vol.39 (2), p.114-120 |
|---|---|
| Hauptverfasser: | , , , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 120 |
|---|---|
| container_issue | 2 |
| container_start_page | 114 |
| container_title | Immunogenetics (New York) |
| container_volume | 39 |
| creator | D'ALFONSO, S CAPPELLO, N BORELLI, I MAZZOLA, G PERUCCIO, D GIORDANO, M CASCINO, I TOSI, R MOMIGLIANO RICHIARDI, P |
| description | A supratype analysis of a North Italian population was performed, using 16 polymorphisms in the HLA region spanning the HLA-A-DP segment. Fourteen supratypes were identified, mostly corresponding to those found in other Caucasoid populations. The degree of their conservation both within the B-DR/DQ region and in the regions telomeric and centromeric from HLA-A and DP was evaluated and linkage disequilibria among several DR and DP alleles were identified. Notably, the degree of association with DP increased when the DR marker was part of a conserved B-DR/DQ supratype. These data are relevant to the definition of the genetic structure of the population and to the prediction of probabilities of histocompatibility matching between unrelated individuals. |
| doi_str_mv | 10.1007/BF00188614 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_76337296</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>16894239</sourcerecordid><originalsourceid>FETCH-LOGICAL-c342t-35cc6fb4fcfc08e79544e2f54a63c4c9337ee564ae0a819c54874a4bcc5ad33a3</originalsourceid><addsrcrecordid>eNqF0L1Lw0AYBvBDlFqri7uQQRSE6H289zXWYm2h4KJzeHu9g0iaxLtk8L830lBHp2d4fjzDQ8g1o4-MUv30vKSUGaMYnJApA8Fzxhk7JVNKrci1ZuycXKT0OShpuZqQieFagYQpuV9t5lnq24jdd-tTVtYZ1tm6w6ocsm3avsKubOpLchawSv5qzBn5WL68L1b55u11vZhvcieAd7mQzqmwheCCo8ZrKwE8DxJQCQfOCqG9lwrQUzTMOglGA8LWOYk7IVDMyN1ht43NV-9TV-zL5HxVYe2bPhVaDRPcqn8hU8YCF3aADwfoYpNS9KFoY7nH-F0wWvzeV_zdN-CbcbXf7v3uSMe_hv527DE5rELE2pXpyIThkkoqfgCIYXSp</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>16894239</pqid></control><display><type>article</type><title>HLA supratypes in an Italian population</title><source>MEDLINE</source><source>SpringerLink Journals - AutoHoldings</source><creator>D'ALFONSO, S ; CAPPELLO, N ; BORELLI, I ; MAZZOLA, G ; PERUCCIO, D ; GIORDANO, M ; CASCINO, I ; TOSI, R ; MOMIGLIANO RICHIARDI, P</creator><creatorcontrib>D'ALFONSO, S ; CAPPELLO, N ; BORELLI, I ; MAZZOLA, G ; PERUCCIO, D ; GIORDANO, M ; CASCINO, I ; TOSI, R ; MOMIGLIANO RICHIARDI, P</creatorcontrib><description>A supratype analysis of a North Italian population was performed, using 16 polymorphisms in the HLA region spanning the HLA-A-DP segment. Fourteen supratypes were identified, mostly corresponding to those found in other Caucasoid populations. The degree of their conservation both within the B-DR/DQ region and in the regions telomeric and centromeric from HLA-A and DP was evaluated and linkage disequilibria among several DR and DP alleles were identified. Notably, the degree of association with DP increased when the DR marker was part of a conserved B-DR/DQ supratype. These data are relevant to the definition of the genetic structure of the population and to the prediction of probabilities of histocompatibility matching between unrelated individuals.</description><identifier>ISSN: 0093-7711</identifier><identifier>EISSN: 1432-1211</identifier><identifier>DOI: 10.1007/BF00188614</identifier><identifier>PMID: 8276454</identifier><identifier>CODEN: IMNGBK</identifier><language>eng</language><publisher>Heidelberg: Springer</publisher><subject>Antigens ; Biological and medical sciences ; Fundamental and applied biological sciences. Psychology ; Fundamental immunology ; Histocompatibility antigens (hla, h-2 and other systems) ; HLA Antigens - genetics ; HLA-A Antigens - genetics ; HLA-B Antigens - genetics ; HLA-DP Antigens - genetics ; HLA-DQ Antigens - genetics ; HLA-DR Antigens - genetics ; Humans ; Italy ; Molecular immunology ; Polymorphism, Genetic</subject><ispartof>Immunogenetics (New York), 1994, Vol.39 (2), p.114-120</ispartof><rights>1994 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c342t-35cc6fb4fcfc08e79544e2f54a63c4c9337ee564ae0a819c54874a4bcc5ad33a3</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,4010,27900,27901,27902</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=3825050$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/8276454$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>D'ALFONSO, S</creatorcontrib><creatorcontrib>CAPPELLO, N</creatorcontrib><creatorcontrib>BORELLI, I</creatorcontrib><creatorcontrib>MAZZOLA, G</creatorcontrib><creatorcontrib>PERUCCIO, D</creatorcontrib><creatorcontrib>GIORDANO, M</creatorcontrib><creatorcontrib>CASCINO, I</creatorcontrib><creatorcontrib>TOSI, R</creatorcontrib><creatorcontrib>MOMIGLIANO RICHIARDI, P</creatorcontrib><title>HLA supratypes in an Italian population</title><title>Immunogenetics (New York)</title><addtitle>Immunogenetics</addtitle><description>A supratype analysis of a North Italian population was performed, using 16 polymorphisms in the HLA region spanning the HLA-A-DP segment. Fourteen supratypes were identified, mostly corresponding to those found in other Caucasoid populations. The degree of their conservation both within the B-DR/DQ region and in the regions telomeric and centromeric from HLA-A and DP was evaluated and linkage disequilibria among several DR and DP alleles were identified. Notably, the degree of association with DP increased when the DR marker was part of a conserved B-DR/DQ supratype. These data are relevant to the definition of the genetic structure of the population and to the prediction of probabilities of histocompatibility matching between unrelated individuals.</description><subject>Antigens</subject><subject>Biological and medical sciences</subject><subject>Fundamental and applied biological sciences. Psychology</subject><subject>Fundamental immunology</subject><subject>Histocompatibility antigens (hla, h-2 and other systems)</subject><subject>HLA Antigens - genetics</subject><subject>HLA-A Antigens - genetics</subject><subject>HLA-B Antigens - genetics</subject><subject>HLA-DP Antigens - genetics</subject><subject>HLA-DQ Antigens - genetics</subject><subject>HLA-DR Antigens - genetics</subject><subject>Humans</subject><subject>Italy</subject><subject>Molecular immunology</subject><subject>Polymorphism, Genetic</subject><issn>0093-7711</issn><issn>1432-1211</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1994</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqF0L1Lw0AYBvBDlFqri7uQQRSE6H289zXWYm2h4KJzeHu9g0iaxLtk8L830lBHp2d4fjzDQ8g1o4-MUv30vKSUGaMYnJApA8Fzxhk7JVNKrci1ZuycXKT0OShpuZqQieFagYQpuV9t5lnq24jdd-tTVtYZ1tm6w6ocsm3avsKubOpLchawSv5qzBn5WL68L1b55u11vZhvcieAd7mQzqmwheCCo8ZrKwE8DxJQCQfOCqG9lwrQUzTMOglGA8LWOYk7IVDMyN1ht43NV-9TV-zL5HxVYe2bPhVaDRPcqn8hU8YCF3aADwfoYpNS9KFoY7nH-F0wWvzeV_zdN-CbcbXf7v3uSMe_hv527DE5rELE2pXpyIThkkoqfgCIYXSp</recordid><startdate>1994</startdate><enddate>1994</enddate><creator>D'ALFONSO, S</creator><creator>CAPPELLO, N</creator><creator>BORELLI, I</creator><creator>MAZZOLA, G</creator><creator>PERUCCIO, D</creator><creator>GIORDANO, M</creator><creator>CASCINO, I</creator><creator>TOSI, R</creator><creator>MOMIGLIANO RICHIARDI, P</creator><general>Springer</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7T5</scope><scope>H94</scope><scope>7X8</scope></search><sort><creationdate>1994</creationdate><title>HLA supratypes in an Italian population</title><author>D'ALFONSO, S ; CAPPELLO, N ; BORELLI, I ; MAZZOLA, G ; PERUCCIO, D ; GIORDANO, M ; CASCINO, I ; TOSI, R ; MOMIGLIANO RICHIARDI, P</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c342t-35cc6fb4fcfc08e79544e2f54a63c4c9337ee564ae0a819c54874a4bcc5ad33a3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1994</creationdate><topic>Antigens</topic><topic>Biological and medical sciences</topic><topic>Fundamental and applied biological sciences. Psychology</topic><topic>Fundamental immunology</topic><topic>Histocompatibility antigens (hla, h-2 and other systems)</topic><topic>HLA Antigens - genetics</topic><topic>HLA-A Antigens - genetics</topic><topic>HLA-B Antigens - genetics</topic><topic>HLA-DP Antigens - genetics</topic><topic>HLA-DQ Antigens - genetics</topic><topic>HLA-DR Antigens - genetics</topic><topic>Humans</topic><topic>Italy</topic><topic>Molecular immunology</topic><topic>Polymorphism, Genetic</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>D'ALFONSO, S</creatorcontrib><creatorcontrib>CAPPELLO, N</creatorcontrib><creatorcontrib>BORELLI, I</creatorcontrib><creatorcontrib>MAZZOLA, G</creatorcontrib><creatorcontrib>PERUCCIO, D</creatorcontrib><creatorcontrib>GIORDANO, M</creatorcontrib><creatorcontrib>CASCINO, I</creatorcontrib><creatorcontrib>TOSI, R</creatorcontrib><creatorcontrib>MOMIGLIANO RICHIARDI, P</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Immunology Abstracts</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>Immunogenetics (New York)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>D'ALFONSO, S</au><au>CAPPELLO, N</au><au>BORELLI, I</au><au>MAZZOLA, G</au><au>PERUCCIO, D</au><au>GIORDANO, M</au><au>CASCINO, I</au><au>TOSI, R</au><au>MOMIGLIANO RICHIARDI, P</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>HLA supratypes in an Italian population</atitle><jtitle>Immunogenetics (New York)</jtitle><addtitle>Immunogenetics</addtitle><date>1994</date><risdate>1994</risdate><volume>39</volume><issue>2</issue><spage>114</spage><epage>120</epage><pages>114-120</pages><issn>0093-7711</issn><eissn>1432-1211</eissn><coden>IMNGBK</coden><abstract>A supratype analysis of a North Italian population was performed, using 16 polymorphisms in the HLA region spanning the HLA-A-DP segment. Fourteen supratypes were identified, mostly corresponding to those found in other Caucasoid populations. The degree of their conservation both within the B-DR/DQ region and in the regions telomeric and centromeric from HLA-A and DP was evaluated and linkage disequilibria among several DR and DP alleles were identified. Notably, the degree of association with DP increased when the DR marker was part of a conserved B-DR/DQ supratype. These data are relevant to the definition of the genetic structure of the population and to the prediction of probabilities of histocompatibility matching between unrelated individuals.</abstract><cop>Heidelberg</cop><cop>Berlin</cop><pub>Springer</pub><pmid>8276454</pmid><doi>10.1007/BF00188614</doi><tpages>7</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0093-7711 |
| ispartof | Immunogenetics (New York), 1994, Vol.39 (2), p.114-120 |
| issn | 0093-7711 1432-1211 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_76337296 |
| source | MEDLINE; SpringerLink Journals - AutoHoldings |
| subjects | Antigens Biological and medical sciences Fundamental and applied biological sciences. Psychology Fundamental immunology Histocompatibility antigens (hla, h-2 and other systems) HLA Antigens - genetics HLA-A Antigens - genetics HLA-B Antigens - genetics HLA-DP Antigens - genetics HLA-DQ Antigens - genetics HLA-DR Antigens - genetics Humans Italy Molecular immunology Polymorphism, Genetic |
| title | HLA supratypes in an Italian population |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-09T09%3A05%3A18IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=HLA%20supratypes%20in%20an%20Italian%20population&rft.jtitle=Immunogenetics%20(New%20York)&rft.au=D'ALFONSO,%20S&rft.date=1994&rft.volume=39&rft.issue=2&rft.spage=114&rft.epage=120&rft.pages=114-120&rft.issn=0093-7711&rft.eissn=1432-1211&rft.coden=IMNGBK&rft_id=info:doi/10.1007/BF00188614&rft_dat=%3Cproquest_cross%3E16894239%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=16894239&rft_id=info:pmid/8276454&rfr_iscdi=true |