Diagnostic value of C-reactive protein in acute appendicitis
Serum C-reactive protein was measured in 56 patients hospitalized with a suspected diagnosis of acute appendicitis. Based on these determinations, four groups of patients were defined: Group A = 26 patients with acute appendicitis who had a C-reactive protein level higher than 2.5 mg/dl. Group B = 4...
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| Veröffentlicht in: | Diseases of the colon & rectum 1994, Vol.37 (1), p.49-51 |
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| container_title | Diseases of the colon & rectum |
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| creator | ALBU, E MILLER, B. M YOUNG CHOI SANJIV LAKHANPAL MURTHY, R. N GERST, P. H |
| description | Serum C-reactive protein was measured in 56 patients hospitalized with a suspected diagnosis of acute appendicitis. Based on these determinations, four groups of patients were defined: Group A = 26 patients with acute appendicitis who had a C-reactive protein level higher than 2.5 mg/dl. Group B = 4 patients with a C-reactive protein level lower than 2.5 mg/dl who, after surgery based on a presumed diagnosis of acute appendicitis, were found to have a normal appendix. Group C = 22 patients with nonspecific abdominal pain, 18 (72 percent) of whom had an elevated C-reactive protein level, although in only 4 (7.1 percent) were these levels higher than 2.5 percent mg/dl. Group D = 4 patients who had diseases other than acute appendicitis. It is concluded that an increase in C-reactive protein levels to more than 2.5 mg/dl is not a definite indicator of acute appendicitis. However, if the C-reactive protein level in blood drawn 12 hours after the onset of symptoms is less than 2.5 mg/dl, acute appendicitis can be excluded. |
| doi_str_mv | 10.1007/BF02047214 |
| format | Article |
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M ; YOUNG CHOI ; SANJIV LAKHANPAL ; MURTHY, R. N ; GERST, P. H</creator><creatorcontrib>ALBU, E ; MILLER, B. M ; YOUNG CHOI ; SANJIV LAKHANPAL ; MURTHY, R. N ; GERST, P. H</creatorcontrib><description>Serum C-reactive protein was measured in 56 patients hospitalized with a suspected diagnosis of acute appendicitis. Based on these determinations, four groups of patients were defined: Group A = 26 patients with acute appendicitis who had a C-reactive protein level higher than 2.5 mg/dl. Group B = 4 patients with a C-reactive protein level lower than 2.5 mg/dl who, after surgery based on a presumed diagnosis of acute appendicitis, were found to have a normal appendix. Group C = 22 patients with nonspecific abdominal pain, 18 (72 percent) of whom had an elevated C-reactive protein level, although in only 4 (7.1 percent) were these levels higher than 2.5 percent mg/dl. Group D = 4 patients who had diseases other than acute appendicitis. It is concluded that an increase in C-reactive protein levels to more than 2.5 mg/dl is not a definite indicator of acute appendicitis. However, if the C-reactive protein level in blood drawn 12 hours after the onset of symptoms is less than 2.5 mg/dl, acute appendicitis can be excluded.</description><identifier>ISSN: 0012-3706</identifier><identifier>EISSN: 1530-0358</identifier><identifier>DOI: 10.1007/BF02047214</identifier><identifier>PMID: 8287747</identifier><identifier>CODEN: DICRAG</identifier><language>eng</language><publisher>Secaucus, NJ: Springer</publisher><subject>Acute Disease ; Adolescent ; Adult ; Appendicitis - complications ; Appendicitis - diagnosis ; Appendicitis - pathology ; Appendicitis - surgery ; Biological and medical sciences ; Biomarkers - blood ; C-Reactive Protein - analysis ; Child ; Child, Preschool ; Double-Blind Method ; Gangrene ; Gastroenterology. Liver. Pancreas. Abdomen ; Humans ; Intestinal Perforation - diagnosis ; Intestinal Perforation - etiology ; Intestinal Perforation - surgery ; Medical sciences ; Other diseases. Semiology ; Predictive Value of Tests ; Preoperative Care ; Prospective Studies ; Rupture, Spontaneous ; Sensitivity and Specificity ; Stomach. Duodenum. Small intestine. Colon. Rectum. 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M</creatorcontrib><creatorcontrib>YOUNG CHOI</creatorcontrib><creatorcontrib>SANJIV LAKHANPAL</creatorcontrib><creatorcontrib>MURTHY, R. N</creatorcontrib><creatorcontrib>GERST, P. H</creatorcontrib><title>Diagnostic value of C-reactive protein in acute appendicitis</title><title>Diseases of the colon & rectum</title><addtitle>Dis Colon Rectum</addtitle><description>Serum C-reactive protein was measured in 56 patients hospitalized with a suspected diagnosis of acute appendicitis. Based on these determinations, four groups of patients were defined: Group A = 26 patients with acute appendicitis who had a C-reactive protein level higher than 2.5 mg/dl. Group B = 4 patients with a C-reactive protein level lower than 2.5 mg/dl who, after surgery based on a presumed diagnosis of acute appendicitis, were found to have a normal appendix. Group C = 22 patients with nonspecific abdominal pain, 18 (72 percent) of whom had an elevated C-reactive protein level, although in only 4 (7.1 percent) were these levels higher than 2.5 percent mg/dl. Group D = 4 patients who had diseases other than acute appendicitis. It is concluded that an increase in C-reactive protein levels to more than 2.5 mg/dl is not a definite indicator of acute appendicitis. However, if the C-reactive protein level in blood drawn 12 hours after the onset of symptoms is less than 2.5 mg/dl, acute appendicitis can be excluded.</description><subject>Acute Disease</subject><subject>Adolescent</subject><subject>Adult</subject><subject>Appendicitis - complications</subject><subject>Appendicitis - diagnosis</subject><subject>Appendicitis - pathology</subject><subject>Appendicitis - surgery</subject><subject>Biological and medical sciences</subject><subject>Biomarkers - blood</subject><subject>C-Reactive Protein - analysis</subject><subject>Child</subject><subject>Child, Preschool</subject><subject>Double-Blind Method</subject><subject>Gangrene</subject><subject>Gastroenterology. Liver. Pancreas. Abdomen</subject><subject>Humans</subject><subject>Intestinal Perforation - diagnosis</subject><subject>Intestinal Perforation - etiology</subject><subject>Intestinal Perforation - surgery</subject><subject>Medical sciences</subject><subject>Other diseases. Semiology</subject><subject>Predictive Value of Tests</subject><subject>Preoperative Care</subject><subject>Prospective Studies</subject><subject>Rupture, Spontaneous</subject><subject>Sensitivity and Specificity</subject><subject>Stomach. Duodenum. Small intestine. Colon. Rectum. Anus</subject><issn>0012-3706</issn><issn>1530-0358</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1994</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpFkEFLxDAQhYMo67p68S70IB6E6iRpkyx40eqqsOBFz2WaTiXSbWvTLvjvjWxZYWAY3sebx2PsnMMNB9C3DysQkGjBkwM256mEGGRqDtkcgItYalDH7MT7r3AGUM_YzAijdaLn7O7R4WfT-sHZaIv1SFFbRVncE9rBbSnq-nYg10Rh0I4DRdh11JTOusH5U3ZUYe3pbNoL9rF6es9e4vXb82t2v46t5HyIK-Qkl8pahMKUaomoE1laXVgKb4pCiTQFY2SqC7RqCSJIZSIkN1JxpEQu2NXON6T5HskP-cZ5S3WNDbWjz7WSMgUpAni9A23fet9TlXe922D_k3PI_6rK_6sK8MXkOhYbKvfo1E3QLycdvcW66rGxzu-xhIPhSslfTOtvWw</recordid><startdate>1994</startdate><enddate>1994</enddate><creator>ALBU, E</creator><creator>MILLER, B. M</creator><creator>YOUNG CHOI</creator><creator>SANJIV LAKHANPAL</creator><creator>MURTHY, R. N</creator><creator>GERST, P. H</creator><general>Springer</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>1994</creationdate><title>Diagnostic value of C-reactive protein in acute appendicitis</title><author>ALBU, E ; MILLER, B. M ; YOUNG CHOI ; SANJIV LAKHANPAL ; MURTHY, R. N ; GERST, P. H</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c311t-fa1e396cca0b8d69aa743dc7bceeacbb6255088357bac6902c7bd42318361ae43</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1994</creationdate><topic>Acute Disease</topic><topic>Adolescent</topic><topic>Adult</topic><topic>Appendicitis - complications</topic><topic>Appendicitis - diagnosis</topic><topic>Appendicitis - pathology</topic><topic>Appendicitis - surgery</topic><topic>Biological and medical sciences</topic><topic>Biomarkers - blood</topic><topic>C-Reactive Protein - analysis</topic><topic>Child</topic><topic>Child, Preschool</topic><topic>Double-Blind Method</topic><topic>Gangrene</topic><topic>Gastroenterology. Liver. Pancreas. Abdomen</topic><topic>Humans</topic><topic>Intestinal Perforation - diagnosis</topic><topic>Intestinal Perforation - etiology</topic><topic>Intestinal Perforation - surgery</topic><topic>Medical sciences</topic><topic>Other diseases. Semiology</topic><topic>Predictive Value of Tests</topic><topic>Preoperative Care</topic><topic>Prospective Studies</topic><topic>Rupture, Spontaneous</topic><topic>Sensitivity and Specificity</topic><topic>Stomach. Duodenum. Small intestine. Colon. Rectum. Anus</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>ALBU, E</creatorcontrib><creatorcontrib>MILLER, B. M</creatorcontrib><creatorcontrib>YOUNG CHOI</creatorcontrib><creatorcontrib>SANJIV LAKHANPAL</creatorcontrib><creatorcontrib>MURTHY, R. N</creatorcontrib><creatorcontrib>GERST, P. 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H</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Diagnostic value of C-reactive protein in acute appendicitis</atitle><jtitle>Diseases of the colon & rectum</jtitle><addtitle>Dis Colon Rectum</addtitle><date>1994</date><risdate>1994</risdate><volume>37</volume><issue>1</issue><spage>49</spage><epage>51</epage><pages>49-51</pages><issn>0012-3706</issn><eissn>1530-0358</eissn><coden>DICRAG</coden><abstract>Serum C-reactive protein was measured in 56 patients hospitalized with a suspected diagnosis of acute appendicitis. Based on these determinations, four groups of patients were defined: Group A = 26 patients with acute appendicitis who had a C-reactive protein level higher than 2.5 mg/dl. Group B = 4 patients with a C-reactive protein level lower than 2.5 mg/dl who, after surgery based on a presumed diagnosis of acute appendicitis, were found to have a normal appendix. Group C = 22 patients with nonspecific abdominal pain, 18 (72 percent) of whom had an elevated C-reactive protein level, although in only 4 (7.1 percent) were these levels higher than 2.5 percent mg/dl. Group D = 4 patients who had diseases other than acute appendicitis. It is concluded that an increase in C-reactive protein levels to more than 2.5 mg/dl is not a definite indicator of acute appendicitis. However, if the C-reactive protein level in blood drawn 12 hours after the onset of symptoms is less than 2.5 mg/dl, acute appendicitis can be excluded.</abstract><cop>Secaucus, NJ</cop><pub>Springer</pub><pmid>8287747</pmid><doi>10.1007/BF02047214</doi><tpages>3</tpages></addata></record> |
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| source | MEDLINE; Journals@Ovid Complete; SpringerLink Journals - AutoHoldings |
| subjects | Acute Disease Adolescent Adult Appendicitis - complications Appendicitis - diagnosis Appendicitis - pathology Appendicitis - surgery Biological and medical sciences Biomarkers - blood C-Reactive Protein - analysis Child Child, Preschool Double-Blind Method Gangrene Gastroenterology. Liver. Pancreas. Abdomen Humans Intestinal Perforation - diagnosis Intestinal Perforation - etiology Intestinal Perforation - surgery Medical sciences Other diseases. Semiology Predictive Value of Tests Preoperative Care Prospective Studies Rupture, Spontaneous Sensitivity and Specificity Stomach. Duodenum. Small intestine. Colon. Rectum. Anus |
| title | Diagnostic value of C-reactive protein in acute appendicitis |
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