Adenosine deaminase inhibitor in cardioplegia enhanced function preservation of the hypothermically stored rat heart

Adenosine (ADO) has been shown to be protective to the ischemic-reperfused myocardium. This study tested the hypothesis that inhibition of myocardial adenosine deaminase during cold storage will elevate tissue ADO content, improve the cardiac function, and preserve ATP. The isolated rat hearts (6-9...

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Veröffentlicht in:	Transplantation 1994, Vol.57 (1), p.35-40
Hauptverfasser:	QINGYAN ZHU, XIAOPING YANG, CLAYDON, M. A, HICKS, G. L, WANG, T
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenine - administration & dosage Adenine - analogs & derivatives Adenosine Deaminase Inhibitors Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy Animals Biological and medical sciences Clinical death. Palliative care. Organ gift and preservation Coronary Circulation Heart Arrest, Induced Heart Transplantation - methods Hemodynamics Male Medical sciences Organ Preservation - methods Rats Rats, Sprague-Dawley Time Factors
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