Affinity ranking of influenza neuraminidase mutants with monoclonal antibodies using an optical biosensor comparison with ELISA and slot blot assays

A recently developed alternative to the more traditional techniques for studying antigen-antibody interactions has been examined. This method involves the use of an optical biosensor employing surface plasmon resonance detection. In this system one of the reactants is immobilized on the sensor surfa...

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Veröffentlicht in:	Journal of immunological methods 1994-01, Vol.168 (1), p.91-100
Hauptverfasser:	GRUEN, L. C, MCKIMM-BRESCHKIN, J. L, CALDWELL, J. B, NICE, E. C
Format:	Artikel
Sprache:	eng
Schlagworte:	Antibodies, Monoclonal - immunology Antibodies, Viral - immunology Antigen-Antibody Reactions Antigen-antibody reactions, antigen-antibody complexes, antibody-complement and others. Study of affinity. Antigen presentation Biological and medical sciences Biosensing Techniques Enzyme-Linked Immunosorbent Assay Fundamental and applied biological sciences. Psychology Fundamental immunology Immunoblotting Immunoglobulin Fab Fragments - immunology Influenza A virus - enzymology influenza virus Molecular immunology Mutation Neuraminidase - genetics Neuraminidase - immunology
Online-Zugang:	Volltext
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