Upmodulation by estrogen of HLA class I expression in breast tumor cell lines

The expression of major histocompatibility complex (MHC) class I antigens was studied in five breast carcinoma cell lines before and after treatment with 17-beta estradiol. Increased HLA class I antigen expression correlated with the presence of estrogen receptors. The modulation of expression appea...

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Veröffentlicht in:	Immunogenetics (New York) 1994, Vol.39 (3), p.161-167
Hauptverfasser:	RODRIGUEZ, F, PERAN, F, GARRIDO, F, RUIZ-CABELLO, F
Format:	Artikel
Sprache:	eng
Schlagworte:	Antigens Base Sequence Biological and medical sciences Breast Neoplasms - genetics Breast Neoplasms - immunology Breast Neoplasms - metabolism Carcinoma - genetics Carcinoma - immunology Carcinoma - metabolism DNA-Binding Proteins - metabolism Estradiol - pharmacology Female Fundamental and applied biological sciences. Psychology Fundamental immunology Gene Expression Regulation, Neoplastic - drug effects Histocompatibility antigens (hla, h-2 and other systems) Histocompatibility Antigens Class I - biosynthesis Histocompatibility Antigens Class I - genetics Host Cell Factor C1 Humans Molecular immunology Molecular Sequence Data NF-kappa B - metabolism Octamer Transcription Factor-1 Oligonucleotide Probes - metabolism Regulatory Sequences, Nucleic Acid RNA, Messenger - biosynthesis Transcription Factors - metabolism Tumor Cells, Cultured
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