Experience with a rapid oral metyrapone test and the plasma ACTH content in determining the cause of Cushing's syndrome

A rapid oral metyrapone test (0.5 Gm. every hour for six doses) and a 4 p.m. plasma ACTH bioassay were performed in 20 consecutive patients with Cushing's syndrome. At surgery, 11 had adrenocortical hyperplasia, six had an adrenocortical adenoma, and three had an adrenocortical carcinoma. None...

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