HIV-1 infection of human CD4+ T cells in vitro. Differential induction of apoptosis in these cells

The H9 and CEM CD4+ T cell lines were infected with HIV-1 (NY5/LAV-1 isolate) and monitored for losses in cell viability, syncytium formation, and internucleosomal DNA cleavage (a marker for apoptosis). H9 cells were found to undergo cell death via apoptosis as a result of HIVNY5 infection, but this...

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Veröffentlicht in:	The Journal of immunology (1950) 1994-01, Vol.152 (1), p.330-342
Hauptverfasser:	Martin, SJ, Matear, PM, Vyakarnam, A
Format:	Artikel
Sprache:	eng
Schlagworte:	Ageing, cell death AIDS/HIV Apoptosis - physiology Biological and medical sciences CD4-Positive T-Lymphocytes - microbiology CD4-Positive T-Lymphocytes - physiology CD8 Antigens - blood Cell Line Cell physiology DNA Damage Fundamental and applied biological sciences. Psychology HIV Core Protein p24 - biosynthesis HIV-1 - physiology Humans Molecular and cellular biology T-Lymphocyte Subsets - microbiology T-Lymphocyte Subsets - physiology
Online-Zugang:	Volltext
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