A universally applicable diagnostic approach to filarial and other infections

A universally applicable diagnostic approach to filarial and other infections

Antibody-based assays for the diagnosis of filarial and other infections cannot reliably distinguish between past and current infection, nor can they be used to assess the efficacy of chemotherapy. In this article, Thomas Nutmon, Peter Zimmerman, Joseph Kubofcik and Donna Kostyu discuss how the dete...

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Veröffentlicht in:Parasitology today (Regular ed.) 1994-06, Vol.10 (6), p.239-243
Hauptverfasser: Nutman, T.B., Zimmerman, P.A., Kubofcik, J., Kostyu, D.D.
Format: Artikel
Sprache:eng
Schlagworte:
Brugia malayi
Wuchereria bancrofti
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Zusammenfassung:Antibody-based assays for the diagnosis of filarial and other infections cannot reliably distinguish between past and current infection, nor can they be used to assess the efficacy of chemotherapy. In this article, Thomas Nutmon, Peter Zimmerman, Joseph Kubofcik and Donna Kostyu discuss how the detection of parasite-specific PCR products using on ELISA-based assay may overcome these problems.
ISSN:0169-4758
DOI:10.1016/0169-4758(94)90127-9