Importance of the PaCO(2) from 3 to 6 months after initiation of long-term non-invasive ventilation
The level at which arterial carbon dioxide tension (PaCO(2)) a few months after introduction of long-term non-invasive positive pressure ventilation (NPPV) is associated with a favorable prognosis remains uncertain. Data on 184 post-tuberculosis patients with chronic restrictive ventilatory failure...
Gespeichert in:
| Veröffentlicht in: | Respiratory medicine 2010-12, Vol.104 (12), p.1850-1857 |
|---|---|
| Hauptverfasser: | , , , , , , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 1857 |
|---|---|
| container_issue | 12 |
| container_start_page | 1850 |
| container_title | Respiratory medicine |
| container_volume | 104 |
| creator | Tsuboi, Tomomasa Ohi, Motoharu Oga, Toru Machida, Kazuko Chihara, Yuichi Harada, Yuka Takahashi, Kenichi Sumi, Kensuke Handa, Tomohiro Niimi, Akio Mishima, Michiaki Chin, Kazuo |
| description | The level at which arterial carbon dioxide tension (PaCO(2)) a few months after introduction of long-term non-invasive positive pressure ventilation (NPPV) is associated with a favorable prognosis remains uncertain.
Data on 184 post-tuberculosis patients with chronic restrictive ventilatory failure who were receiving long-term domiciliary NPPV were examined retrospectively. Average PaCO(2) 3-6 months after NPPV (3- to 6-mo PaCO(2)) and potential confounders were analyzed with discontinuation of long-term NPPV as the primary outcome. The effects of 3- to 6-mo PaCO(2) on annual hospitalization rates due to respiratory deterioration from 1 year before to 3 years after the initiation of NPPV were examined. The effect of the difference between the PaCO(2) value at the start of NPPV (0-mo PaCO(2)) and the PaCO(2) value 3- to 6-mo later (d-PaCO(2)) on continuation rates for NPPV was also assessed in patients who initiated NPPV while in a chronic state.
Patients with relatively low 3- to 6-mo PaCO(2) values maintained a relatively low PaCO(2) 6-36 months after NPPV (p |
| doi_str_mv | 10.1016/j.rmed.2010.04.027 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_proquest_miscellaneous_763175276</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>763175276</sourcerecordid><originalsourceid>FETCH-LOGICAL-n991-9bce07bdc35e09ec61a78e9f78d4e4b86037b7f856b463d8edb041818656c88b3</originalsourceid><addsrcrecordid>eNo1kD1PwzAURS0kREvhDzAgb8CQ8Bw7tjOiio9KlcrQvbKTF-oqsUvsVuLfE6BMVzo69w6XkBsGOQMmH3f50GOTFzACEDkU6oxMWcmLjIMUE3IZ4w4AKiHggkwKKLnSmk1Jvej3YUjG10hDS9MW6buZr-6LB9oOoaecpkAl7YNP20hNm3CgzrvkTHLB_1S64D-yEffUB585fzTRHZEe0SfX_VpX5Lw1XcTrU87I-uV5PX_LlqvXxfxpmfmqYlllawRlm5qXCBXWkhmlsWqVbgQKqyVwZVWrS2mF5I3GxoJgmmlZylpry2fk7m92P4TPA8a06V2sseuMx3CIGyU5U2UxxozcnsyDHV_b7AfXm-Fr838L_wYteWMz</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>763175276</pqid></control><display><type>article</type><title>Importance of the PaCO(2) from 3 to 6 months after initiation of long-term non-invasive ventilation</title><source>MEDLINE</source><source>Elsevier ScienceDirect Journals</source><source>Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals</source><creator>Tsuboi, Tomomasa ; Ohi, Motoharu ; Oga, Toru ; Machida, Kazuko ; Chihara, Yuichi ; Harada, Yuka ; Takahashi, Kenichi ; Sumi, Kensuke ; Handa, Tomohiro ; Niimi, Akio ; Mishima, Michiaki ; Chin, Kazuo</creator><creatorcontrib>Tsuboi, Tomomasa ; Ohi, Motoharu ; Oga, Toru ; Machida, Kazuko ; Chihara, Yuichi ; Harada, Yuka ; Takahashi, Kenichi ; Sumi, Kensuke ; Handa, Tomohiro ; Niimi, Akio ; Mishima, Michiaki ; Chin, Kazuo</creatorcontrib><description>The level at which arterial carbon dioxide tension (PaCO(2)) a few months after introduction of long-term non-invasive positive pressure ventilation (NPPV) is associated with a favorable prognosis remains uncertain.
Data on 184 post-tuberculosis patients with chronic restrictive ventilatory failure who were receiving long-term domiciliary NPPV were examined retrospectively. Average PaCO(2) 3-6 months after NPPV (3- to 6-mo PaCO(2)) and potential confounders were analyzed with discontinuation of long-term NPPV as the primary outcome. The effects of 3- to 6-mo PaCO(2) on annual hospitalization rates due to respiratory deterioration from 1 year before to 3 years after the initiation of NPPV were examined. The effect of the difference between the PaCO(2) value at the start of NPPV (0-mo PaCO(2)) and the PaCO(2) value 3- to 6-mo later (d-PaCO(2)) on continuation rates for NPPV was also assessed in patients who initiated NPPV while in a chronic state.
Patients with relatively low 3- to 6-mo PaCO(2) values maintained a relatively low PaCO(2) 6-36 months after NPPV (p < 0.0001) and had significantly better continuation rates (p < 0.03) and lower hospitalization rates from the 1st to 3rd year of NPPV (p = 0.008, 0.049, 0.009, respectively) than those with higher levels. The 0-mo PaCO(2) (p = 0.26) or d-PaCO(2) (p = 0.86) had no predictive value.
A relatively low 3- to 6-mo PaCO(2) value was predictive of long-term use of NPPV. The target values for 3- to 6-mo PaCO(2) may, therefore, be less than 60 mmHg in post-tuberculosis patients, although more studies are needed.</description><identifier>EISSN: 1532-3064</identifier><identifier>DOI: 10.1016/j.rmed.2010.04.027</identifier><identifier>PMID: 20537881</identifier><language>eng</language><publisher>England</publisher><subject>Aged ; Blood Gas Analysis ; Carbon Dioxide - blood ; Chronic Disease ; Female ; Home Care Services, Hospital-Based - standards ; Hospitalization - statistics & numerical data ; Humans ; Male ; Positive-Pressure Respiration - methods ; Prognosis ; Respiratory Function Tests ; Respiratory Insufficiency - blood ; Respiratory Insufficiency - physiopathology ; Respiratory Insufficiency - therapy ; Retrospective Studies ; Time Factors ; Tuberculosis, Pulmonary - blood ; Tuberculosis, Pulmonary - physiopathology ; Tuberculosis, Pulmonary - therapy</subject><ispartof>Respiratory medicine, 2010-12, Vol.104 (12), p.1850-1857</ispartof><rights>Copyright © 2010 Elsevier Ltd. All rights reserved.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27903,27904</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/20537881$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Tsuboi, Tomomasa</creatorcontrib><creatorcontrib>Ohi, Motoharu</creatorcontrib><creatorcontrib>Oga, Toru</creatorcontrib><creatorcontrib>Machida, Kazuko</creatorcontrib><creatorcontrib>Chihara, Yuichi</creatorcontrib><creatorcontrib>Harada, Yuka</creatorcontrib><creatorcontrib>Takahashi, Kenichi</creatorcontrib><creatorcontrib>Sumi, Kensuke</creatorcontrib><creatorcontrib>Handa, Tomohiro</creatorcontrib><creatorcontrib>Niimi, Akio</creatorcontrib><creatorcontrib>Mishima, Michiaki</creatorcontrib><creatorcontrib>Chin, Kazuo</creatorcontrib><title>Importance of the PaCO(2) from 3 to 6 months after initiation of long-term non-invasive ventilation</title><title>Respiratory medicine</title><addtitle>Respir Med</addtitle><description>The level at which arterial carbon dioxide tension (PaCO(2)) a few months after introduction of long-term non-invasive positive pressure ventilation (NPPV) is associated with a favorable prognosis remains uncertain.
Data on 184 post-tuberculosis patients with chronic restrictive ventilatory failure who were receiving long-term domiciliary NPPV were examined retrospectively. Average PaCO(2) 3-6 months after NPPV (3- to 6-mo PaCO(2)) and potential confounders were analyzed with discontinuation of long-term NPPV as the primary outcome. The effects of 3- to 6-mo PaCO(2) on annual hospitalization rates due to respiratory deterioration from 1 year before to 3 years after the initiation of NPPV were examined. The effect of the difference between the PaCO(2) value at the start of NPPV (0-mo PaCO(2)) and the PaCO(2) value 3- to 6-mo later (d-PaCO(2)) on continuation rates for NPPV was also assessed in patients who initiated NPPV while in a chronic state.
Patients with relatively low 3- to 6-mo PaCO(2) values maintained a relatively low PaCO(2) 6-36 months after NPPV (p < 0.0001) and had significantly better continuation rates (p < 0.03) and lower hospitalization rates from the 1st to 3rd year of NPPV (p = 0.008, 0.049, 0.009, respectively) than those with higher levels. The 0-mo PaCO(2) (p = 0.26) or d-PaCO(2) (p = 0.86) had no predictive value.
A relatively low 3- to 6-mo PaCO(2) value was predictive of long-term use of NPPV. The target values for 3- to 6-mo PaCO(2) may, therefore, be less than 60 mmHg in post-tuberculosis patients, although more studies are needed.</description><subject>Aged</subject><subject>Blood Gas Analysis</subject><subject>Carbon Dioxide - blood</subject><subject>Chronic Disease</subject><subject>Female</subject><subject>Home Care Services, Hospital-Based - standards</subject><subject>Hospitalization - statistics & numerical data</subject><subject>Humans</subject><subject>Male</subject><subject>Positive-Pressure Respiration - methods</subject><subject>Prognosis</subject><subject>Respiratory Function Tests</subject><subject>Respiratory Insufficiency - blood</subject><subject>Respiratory Insufficiency - physiopathology</subject><subject>Respiratory Insufficiency - therapy</subject><subject>Retrospective Studies</subject><subject>Time Factors</subject><subject>Tuberculosis, Pulmonary - blood</subject><subject>Tuberculosis, Pulmonary - physiopathology</subject><subject>Tuberculosis, Pulmonary - therapy</subject><issn>1532-3064</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2010</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNo1kD1PwzAURS0kREvhDzAgb8CQ8Bw7tjOiio9KlcrQvbKTF-oqsUvsVuLfE6BMVzo69w6XkBsGOQMmH3f50GOTFzACEDkU6oxMWcmLjIMUE3IZ4w4AKiHggkwKKLnSmk1Jvej3YUjG10hDS9MW6buZr-6LB9oOoaecpkAl7YNP20hNm3CgzrvkTHLB_1S64D-yEffUB585fzTRHZEe0SfX_VpX5Lw1XcTrU87I-uV5PX_LlqvXxfxpmfmqYlllawRlm5qXCBXWkhmlsWqVbgQKqyVwZVWrS2mF5I3GxoJgmmlZylpry2fk7m92P4TPA8a06V2sseuMx3CIGyU5U2UxxozcnsyDHV_b7AfXm-Fr838L_wYteWMz</recordid><startdate>201012</startdate><enddate>201012</enddate><creator>Tsuboi, Tomomasa</creator><creator>Ohi, Motoharu</creator><creator>Oga, Toru</creator><creator>Machida, Kazuko</creator><creator>Chihara, Yuichi</creator><creator>Harada, Yuka</creator><creator>Takahashi, Kenichi</creator><creator>Sumi, Kensuke</creator><creator>Handa, Tomohiro</creator><creator>Niimi, Akio</creator><creator>Mishima, Michiaki</creator><creator>Chin, Kazuo</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7X8</scope></search><sort><creationdate>201012</creationdate><title>Importance of the PaCO(2) from 3 to 6 months after initiation of long-term non-invasive ventilation</title><author>Tsuboi, Tomomasa ; Ohi, Motoharu ; Oga, Toru ; Machida, Kazuko ; Chihara, Yuichi ; Harada, Yuka ; Takahashi, Kenichi ; Sumi, Kensuke ; Handa, Tomohiro ; Niimi, Akio ; Mishima, Michiaki ; Chin, Kazuo</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-n991-9bce07bdc35e09ec61a78e9f78d4e4b86037b7f856b463d8edb041818656c88b3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2010</creationdate><topic>Aged</topic><topic>Blood Gas Analysis</topic><topic>Carbon Dioxide - blood</topic><topic>Chronic Disease</topic><topic>Female</topic><topic>Home Care Services, Hospital-Based - standards</topic><topic>Hospitalization - statistics & numerical data</topic><topic>Humans</topic><topic>Male</topic><topic>Positive-Pressure Respiration - methods</topic><topic>Prognosis</topic><topic>Respiratory Function Tests</topic><topic>Respiratory Insufficiency - blood</topic><topic>Respiratory Insufficiency - physiopathology</topic><topic>Respiratory Insufficiency - therapy</topic><topic>Retrospective Studies</topic><topic>Time Factors</topic><topic>Tuberculosis, Pulmonary - blood</topic><topic>Tuberculosis, Pulmonary - physiopathology</topic><topic>Tuberculosis, Pulmonary - therapy</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Tsuboi, Tomomasa</creatorcontrib><creatorcontrib>Ohi, Motoharu</creatorcontrib><creatorcontrib>Oga, Toru</creatorcontrib><creatorcontrib>Machida, Kazuko</creatorcontrib><creatorcontrib>Chihara, Yuichi</creatorcontrib><creatorcontrib>Harada, Yuka</creatorcontrib><creatorcontrib>Takahashi, Kenichi</creatorcontrib><creatorcontrib>Sumi, Kensuke</creatorcontrib><creatorcontrib>Handa, Tomohiro</creatorcontrib><creatorcontrib>Niimi, Akio</creatorcontrib><creatorcontrib>Mishima, Michiaki</creatorcontrib><creatorcontrib>Chin, Kazuo</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>MEDLINE - Academic</collection><jtitle>Respiratory medicine</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Tsuboi, Tomomasa</au><au>Ohi, Motoharu</au><au>Oga, Toru</au><au>Machida, Kazuko</au><au>Chihara, Yuichi</au><au>Harada, Yuka</au><au>Takahashi, Kenichi</au><au>Sumi, Kensuke</au><au>Handa, Tomohiro</au><au>Niimi, Akio</au><au>Mishima, Michiaki</au><au>Chin, Kazuo</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Importance of the PaCO(2) from 3 to 6 months after initiation of long-term non-invasive ventilation</atitle><jtitle>Respiratory medicine</jtitle><addtitle>Respir Med</addtitle><date>2010-12</date><risdate>2010</risdate><volume>104</volume><issue>12</issue><spage>1850</spage><epage>1857</epage><pages>1850-1857</pages><eissn>1532-3064</eissn><abstract>The level at which arterial carbon dioxide tension (PaCO(2)) a few months after introduction of long-term non-invasive positive pressure ventilation (NPPV) is associated with a favorable prognosis remains uncertain.
Data on 184 post-tuberculosis patients with chronic restrictive ventilatory failure who were receiving long-term domiciliary NPPV were examined retrospectively. Average PaCO(2) 3-6 months after NPPV (3- to 6-mo PaCO(2)) and potential confounders were analyzed with discontinuation of long-term NPPV as the primary outcome. The effects of 3- to 6-mo PaCO(2) on annual hospitalization rates due to respiratory deterioration from 1 year before to 3 years after the initiation of NPPV were examined. The effect of the difference between the PaCO(2) value at the start of NPPV (0-mo PaCO(2)) and the PaCO(2) value 3- to 6-mo later (d-PaCO(2)) on continuation rates for NPPV was also assessed in patients who initiated NPPV while in a chronic state.
Patients with relatively low 3- to 6-mo PaCO(2) values maintained a relatively low PaCO(2) 6-36 months after NPPV (p < 0.0001) and had significantly better continuation rates (p < 0.03) and lower hospitalization rates from the 1st to 3rd year of NPPV (p = 0.008, 0.049, 0.009, respectively) than those with higher levels. The 0-mo PaCO(2) (p = 0.26) or d-PaCO(2) (p = 0.86) had no predictive value.
A relatively low 3- to 6-mo PaCO(2) value was predictive of long-term use of NPPV. The target values for 3- to 6-mo PaCO(2) may, therefore, be less than 60 mmHg in post-tuberculosis patients, although more studies are needed.</abstract><cop>England</cop><pmid>20537881</pmid><doi>10.1016/j.rmed.2010.04.027</doi><tpages>8</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | EISSN: 1532-3064 |
| ispartof | Respiratory medicine, 2010-12, Vol.104 (12), p.1850-1857 |
| issn | 1532-3064 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_763175276 |
| source | MEDLINE; Elsevier ScienceDirect Journals; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals |
| subjects | Aged Blood Gas Analysis Carbon Dioxide - blood Chronic Disease Female Home Care Services, Hospital-Based - standards Hospitalization - statistics & numerical data Humans Male Positive-Pressure Respiration - methods Prognosis Respiratory Function Tests Respiratory Insufficiency - blood Respiratory Insufficiency - physiopathology Respiratory Insufficiency - therapy Retrospective Studies Time Factors Tuberculosis, Pulmonary - blood Tuberculosis, Pulmonary - physiopathology Tuberculosis, Pulmonary - therapy |
| title | Importance of the PaCO(2) from 3 to 6 months after initiation of long-term non-invasive ventilation |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-25T19%3A29%3A02IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Importance%20of%20the%20PaCO(2)%20from%203%20to%206%20months%20after%20initiation%20of%20long-term%20non-invasive%20ventilation&rft.jtitle=Respiratory%20medicine&rft.au=Tsuboi,%20Tomomasa&rft.date=2010-12&rft.volume=104&rft.issue=12&rft.spage=1850&rft.epage=1857&rft.pages=1850-1857&rft.eissn=1532-3064&rft_id=info:doi/10.1016/j.rmed.2010.04.027&rft_dat=%3Cproquest_pubme%3E763175276%3C/proquest_pubme%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=763175276&rft_id=info:pmid/20537881&rfr_iscdi=true |