The effect of cortisone on the intermediary metabolism of epiphyseal cartilage from rats

Total glucose stores per cell are reduced by half in tibial epiphyseal cartilage from rats after 3 days of cortisone treatment, and the ability to produce lactate in vitro without added substrate is abolished. Cortisone reduces lactate production from exogenous glucose to 30% of normal. The pentose...

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Veröffentlicht in:	Archives of biochemistry and biophysics 1969-02, Vol.129 (2), p.421-430
Hauptverfasser:	Kunin, Arthur S., Meyer, William L.
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetates Animals Carbon Dioxide - metabolism Carbon Isotopes Cartilage - anatomy & histology Cartilage - growth & development Cartilage - metabolism Citric Acid Cycle Cortisone - pharmacology Depression, Chemical DNA - metabolism Epiphyses - metabolism Glucose - metabolism Glycogen - biosynthesis Glycolysis - drug effects Lactates - biosynthesis Male Pyruvates - metabolism Rats Stimulation, Chemical Tibia
Online-Zugang:	Volltext
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