Colorimetric Determination of Ethambutol
A method has been developed for the separation and determination of ethambutol using cupric ion as a chelating agent. The method is sensitive for routine assay and simple to carry out. The effect of time on color stability, the reproducibility of the method, and the determination of the complexation...
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Veröffentlicht in: | Journal of pharmaceutical sciences 1969-01, Vol.58 (1), p.110-111 |
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container_title | Journal of pharmaceutical sciences |
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creator | Burger, J.M. Pisano, F.D. Nash, R.A. |
description | A method has been developed for the separation and determination of ethambutol using cupric ion as a chelating agent. The method is sensitive for routine assay and simple to carry out. The effect of time on color stability, the reproducibility of the method, and the determination of the complexation ratio have been investigated. |
doi_str_mv | 10.1002/jps.2600580124 |
format | Article |
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The method is sensitive for routine assay and simple to carry out. The effect of time on color stability, the reproducibility of the method, and the determination of the complexation ratio have been investigated.</description><identifier>ISSN: 0022-3549</identifier><identifier>EISSN: 1520-6017</identifier><identifier>DOI: 10.1002/jps.2600580124</identifier><identifier>PMID: 5765816</identifier><language>eng</language><publisher>Washington: Elsevier Inc</publisher><subject>Chelating Agents ; Chromatography ; Colorimetric analysis-spectrophotometer ; Colorimetry ; Column chromatography-separation ; Copper ; Cupric ion chelation-ethambutol ; Ethambutol - analysis ; Methods ; Spectrophotometry</subject><ispartof>Journal of pharmaceutical sciences, 1969-01, Vol.58 (1), p.110-111</ispartof><rights>1969 Wiley-Liss, Inc., A Wiley Company</rights><rights>Copyright © 1969 Wiley‐Liss, Inc., A Wiley Company</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c4274-ea52197b590167dac4eeab890f103e5eb19848556f3dc52039d9173e213638973</citedby><cites>FETCH-LOGICAL-c4274-ea52197b590167dac4eeab890f103e5eb19848556f3dc52039d9173e213638973</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1002%2Fjps.2600580124$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1002%2Fjps.2600580124$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,776,780,1411,27901,27902,45550,45551</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/5765816$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Burger, J.M.</creatorcontrib><creatorcontrib>Pisano, F.D.</creatorcontrib><creatorcontrib>Nash, R.A.</creatorcontrib><title>Colorimetric Determination of Ethambutol</title><title>Journal of pharmaceutical sciences</title><addtitle>J. Pharm. Sci</addtitle><description>A method has been developed for the separation and determination of ethambutol using cupric ion as a chelating agent. The method is sensitive for routine assay and simple to carry out. The effect of time on color stability, the reproducibility of the method, and the determination of the complexation ratio have been investigated.</description><subject>Chelating Agents</subject><subject>Chromatography</subject><subject>Colorimetric analysis-spectrophotometer</subject><subject>Colorimetry</subject><subject>Column chromatography-separation</subject><subject>Copper</subject><subject>Cupric ion chelation-ethambutol</subject><subject>Ethambutol - analysis</subject><subject>Methods</subject><subject>Spectrophotometry</subject><issn>0022-3549</issn><issn>1520-6017</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1969</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkE1P3DAQhq2qCBbaa29Ie6p6yTK2Yzs-Vrt8agWVCmpvluNMVEOy3tpZPv59jbICcag4zWGe99XMQ8gXCjMKwI5u12nGJICogLLyA5lQwaCQQNVHMskAK7go9R7ZT-kWACQIsUt2hZKionJCvs1DF6LvcYjeTRc4YOz9yg4-rKahnR4Pf2xfb4bQfSI7re0Sft7OA3Jzcnw9PyuWV6fn8-_LwpVMlQVawahWtdBApWqsKxFtXWloKXAUWFNdlZUQsuWNy5dy3WiqODLKJa-04gfk69i7juHvBtNgep8cdp1dYdgkoySHEjjP4GwEXQwpRWzNOv9h45OhYJ7VmKzGvKrJgcNt86busXnBty7yXo_7B9_h0ztt5uLHzzfdxZj1acDHl6yNd0YqroT5dXlqLhiohfy9NIvMVyOPWeW9x2iS87hy2PiIbjBN8P974x_vjY9B</recordid><startdate>196901</startdate><enddate>196901</enddate><creator>Burger, J.M.</creator><creator>Pisano, F.D.</creator><creator>Nash, R.A.</creator><general>Elsevier Inc</general><general>Wiley Subscription Services, Inc., A Wiley Company</general><scope>BSCLL</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>196901</creationdate><title>Colorimetric Determination of Ethambutol</title><author>Burger, J.M. ; Pisano, F.D. ; Nash, R.A.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4274-ea52197b590167dac4eeab890f103e5eb19848556f3dc52039d9173e213638973</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1969</creationdate><topic>Chelating Agents</topic><topic>Chromatography</topic><topic>Colorimetric analysis-spectrophotometer</topic><topic>Colorimetry</topic><topic>Column chromatography-separation</topic><topic>Copper</topic><topic>Cupric ion chelation-ethambutol</topic><topic>Ethambutol - analysis</topic><topic>Methods</topic><topic>Spectrophotometry</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Burger, J.M.</creatorcontrib><creatorcontrib>Pisano, F.D.</creatorcontrib><creatorcontrib>Nash, R.A.</creatorcontrib><collection>Istex</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of pharmaceutical sciences</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Burger, J.M.</au><au>Pisano, F.D.</au><au>Nash, R.A.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Colorimetric Determination of Ethambutol</atitle><jtitle>Journal of pharmaceutical sciences</jtitle><addtitle>J. Pharm. Sci</addtitle><date>1969-01</date><risdate>1969</risdate><volume>58</volume><issue>1</issue><spage>110</spage><epage>111</epage><pages>110-111</pages><issn>0022-3549</issn><eissn>1520-6017</eissn><abstract>A method has been developed for the separation and determination of ethambutol using cupric ion as a chelating agent. The method is sensitive for routine assay and simple to carry out. The effect of time on color stability, the reproducibility of the method, and the determination of the complexation ratio have been investigated.</abstract><cop>Washington</cop><pub>Elsevier Inc</pub><pmid>5765816</pmid><doi>10.1002/jps.2600580124</doi><tpages>2</tpages></addata></record> |
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source | MEDLINE; Wiley Online Library Journals Frontfile Complete; Alma/SFX Local Collection |
subjects | Chelating Agents Chromatography Colorimetric analysis-spectrophotometer Colorimetry Column chromatography-separation Copper Cupric ion chelation-ethambutol Ethambutol - analysis Methods Spectrophotometry |
title | Colorimetric Determination of Ethambutol |
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