Synaptology of luteinizing hormone-releasing hormone neurons in rat preoptic area
The ultrastructural appearance of luteinizing hormone-releasing hormone (LHRH) immunoreactive elements was studied in the medial preoptic area (MPOA) of adult male Fischer 344 rats. The purpose of the study was to determine the distribution and morphology of innervation of the LHRH neuron. Although...
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| Veröffentlicht in: | Peptides (New York, N.Y. : 1980) N.Y. : 1980), 1985-03, Vol.6 (2), p.263-271 |
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| container_title | Peptides (New York, N.Y. : 1980) |
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| creator | Witkin, Joan W. Silverman, Ann-Judith |
| description | The ultrastructural appearance of luteinizing hormone-releasing hormone (LHRH) immunoreactive elements was studied in the medial preoptic area (MPOA) of adult male Fischer 344 rats. The purpose of the study was to determine the distribution and morphology of innervation of the LHRH neuron. Although not numerous, both axo-somatic and axo-dendritic synapses were present and generally of the asymmetric (Gray's II) category. Analyses of 56 profiles of 11 separate perikarya revealed only 7 axo-somatic terminals. The synaptic input to LHRH dendrites was a fraction of that to non-identified dendrites in the same electron micrographic fields; 0.4% of LHRH dendritic membrane was in synaptic contact compared to 6.6% of nonidentified dendritic membrane. In addition to receiving an input, LHRH processes were also seen to make synapses onto non-immunoreactive elements. Close examination of this material for evidence of contact between LHRH elements revealed two clear examples of synaptic interaction and several instances of close association in which no other elements intervened. |
| doi_str_mv | 10.1016/0196-9781(85)90050-6 |
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The purpose of the study was to determine the distribution and morphology of innervation of the LHRH neuron. Although not numerous, both axo-somatic and axo-dendritic synapses were present and generally of the asymmetric (Gray's II) category. Analyses of 56 profiles of 11 separate perikarya revealed only 7 axo-somatic terminals. The synaptic input to LHRH dendrites was a fraction of that to non-identified dendrites in the same electron micrographic fields; 0.4% of LHRH dendritic membrane was in synaptic contact compared to 6.6% of nonidentified dendritic membrane. In addition to receiving an input, LHRH processes were also seen to make synapses onto non-immunoreactive elements. 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Urophysis ; Luteinizing hormone releasing hormone (LHRH) ; Male ; Male rat brain ; Medial preoptic area ; Microscopy, Electron ; Neurons - ultrastructure ; Preoptic Area - metabolism ; Preoptic Area - ultrastructure ; Rats ; Rats, Inbred F344 ; Synapse ; Synapses - ultrastructure ; Ultrastructure ; Vertebrates: endocrinology</subject><ispartof>Peptides (New York, N.Y. : 1980), 1985-03, Vol.6 (2), p.263-271</ispartof><rights>1985</rights><rights>1986 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c452t-6e51c68a45f8d6577f424a37bdeab199940f6b58a5701a40af83783cc84417143</citedby><cites>FETCH-LOGICAL-c452t-6e51c68a45f8d6577f424a37bdeab199940f6b58a5701a40af83783cc84417143</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/0196-9781(85)90050-6$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,780,784,3550,27924,27925,45995</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=8500750$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/3898038$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Witkin, Joan W.</creatorcontrib><creatorcontrib>Silverman, Ann-Judith</creatorcontrib><title>Synaptology of luteinizing hormone-releasing hormone neurons in rat preoptic area</title><title>Peptides (New York, N.Y. : 1980)</title><addtitle>Peptides</addtitle><description>The ultrastructural appearance of luteinizing hormone-releasing hormone (LHRH) immunoreactive elements was studied in the medial preoptic area (MPOA) of adult male Fischer 344 rats. The purpose of the study was to determine the distribution and morphology of innervation of the LHRH neuron. Although not numerous, both axo-somatic and axo-dendritic synapses were present and generally of the asymmetric (Gray's II) category. Analyses of 56 profiles of 11 separate perikarya revealed only 7 axo-somatic terminals. The synaptic input to LHRH dendrites was a fraction of that to non-identified dendrites in the same electron micrographic fields; 0.4% of LHRH dendritic membrane was in synaptic contact compared to 6.6% of nonidentified dendritic membrane. In addition to receiving an input, LHRH processes were also seen to make synapses onto non-immunoreactive elements. Close examination of this material for evidence of contact between LHRH elements revealed two clear examples of synaptic interaction and several instances of close association in which no other elements intervened.</description><subject>Animals</subject><subject>Axons - ultrastructure</subject><subject>Biological and medical sciences</subject><subject>Dendrites - ultrastructure</subject><subject>Fundamental and applied biological sciences. Psychology</subject><subject>Gonadotropin-Releasing Hormone - metabolism</subject><subject>Hormones and neuropeptides. Regulation</subject><subject>Hypothalamus. Hypophysis. Epiphysis. Urophysis</subject><subject>Luteinizing hormone releasing hormone (LHRH)</subject><subject>Male</subject><subject>Male rat brain</subject><subject>Medial preoptic area</subject><subject>Microscopy, Electron</subject><subject>Neurons - ultrastructure</subject><subject>Preoptic Area - metabolism</subject><subject>Preoptic Area - ultrastructure</subject><subject>Rats</subject><subject>Rats, Inbred F344</subject><subject>Synapse</subject><subject>Synapses - ultrastructure</subject><subject>Ultrastructure</subject><subject>Vertebrates: endocrinology</subject><issn>0196-9781</issn><issn>1873-5169</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1985</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kE1rFEEQhhtRkk3MP1CYg4geJlbv9OdFkGCMEJAQPTe1PTWxw2z3pHtGWH99ZrPLklNOBVXP-1I8jL3jcM6Bqy_AraqtNvyTkZ8tgIRavWILbnRTS67sa7Y4IMfspJR7ABDCmiN21BhroDELdnO7iTiMqU93myp1VT-NFGL4H-Jd9TfldYpUZ-oJy7NNFWnKKZYqxCrjWA2Z0jAGX2EmfMvedNgXOtvPU_bn8vvvi6v6-tePnxffrmsv5HKsFUnulUEhO9MqqXUnlgIbvWoJV9xaK6BTK2lQauAoADvTaNN4b4TgmovmlH3c9Q45PUxURrcOxVPfY6Q0FafV0ijZyBkUO9DnVEqmzg05rDFvHAe3Nem2mtxWkzPSPZl0ao693_dPqzW1h9Be3Xz_sL9j8dh3GaMP5YAZCaAlzNjXHUazi3-Bsis-UPTUhkx-dG0KL__xCOoTj34</recordid><startdate>198503</startdate><enddate>198503</enddate><creator>Witkin, Joan W.</creator><creator>Silverman, Ann-Judith</creator><general>Elsevier Inc</general><general>Elsevier Science</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>198503</creationdate><title>Synaptology of luteinizing hormone-releasing hormone neurons in rat preoptic area</title><author>Witkin, Joan W. ; Silverman, Ann-Judith</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c452t-6e51c68a45f8d6577f424a37bdeab199940f6b58a5701a40af83783cc84417143</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1985</creationdate><topic>Animals</topic><topic>Axons - ultrastructure</topic><topic>Biological and medical sciences</topic><topic>Dendrites - ultrastructure</topic><topic>Fundamental and applied biological sciences. Psychology</topic><topic>Gonadotropin-Releasing Hormone - metabolism</topic><topic>Hormones and neuropeptides. Regulation</topic><topic>Hypothalamus. Hypophysis. Epiphysis. Urophysis</topic><topic>Luteinizing hormone releasing hormone (LHRH)</topic><topic>Male</topic><topic>Male rat brain</topic><topic>Medial preoptic area</topic><topic>Microscopy, Electron</topic><topic>Neurons - ultrastructure</topic><topic>Preoptic Area - metabolism</topic><topic>Preoptic Area - ultrastructure</topic><topic>Rats</topic><topic>Rats, Inbred F344</topic><topic>Synapse</topic><topic>Synapses - ultrastructure</topic><topic>Ultrastructure</topic><topic>Vertebrates: endocrinology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Witkin, Joan W.</creatorcontrib><creatorcontrib>Silverman, Ann-Judith</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Peptides (New York, N.Y. : 1980)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Witkin, Joan W.</au><au>Silverman, Ann-Judith</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Synaptology of luteinizing hormone-releasing hormone neurons in rat preoptic area</atitle><jtitle>Peptides (New York, N.Y. : 1980)</jtitle><addtitle>Peptides</addtitle><date>1985-03</date><risdate>1985</risdate><volume>6</volume><issue>2</issue><spage>263</spage><epage>271</epage><pages>263-271</pages><issn>0196-9781</issn><eissn>1873-5169</eissn><coden>PPTDD5</coden><abstract>The ultrastructural appearance of luteinizing hormone-releasing hormone (LHRH) immunoreactive elements was studied in the medial preoptic area (MPOA) of adult male Fischer 344 rats. The purpose of the study was to determine the distribution and morphology of innervation of the LHRH neuron. Although not numerous, both axo-somatic and axo-dendritic synapses were present and generally of the asymmetric (Gray's II) category. Analyses of 56 profiles of 11 separate perikarya revealed only 7 axo-somatic terminals. The synaptic input to LHRH dendrites was a fraction of that to non-identified dendrites in the same electron micrographic fields; 0.4% of LHRH dendritic membrane was in synaptic contact compared to 6.6% of nonidentified dendritic membrane. In addition to receiving an input, LHRH processes were also seen to make synapses onto non-immunoreactive elements. Close examination of this material for evidence of contact between LHRH elements revealed two clear examples of synaptic interaction and several instances of close association in which no other elements intervened.</abstract><cop>New York, NY</cop><pub>Elsevier Inc</pub><pmid>3898038</pmid><doi>10.1016/0196-9781(85)90050-6</doi><tpages>9</tpages></addata></record> |
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| ispartof | Peptides (New York, N.Y. : 1980), 1985-03, Vol.6 (2), p.263-271 |
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| subjects | Animals Axons - ultrastructure Biological and medical sciences Dendrites - ultrastructure Fundamental and applied biological sciences. Psychology Gonadotropin-Releasing Hormone - metabolism Hormones and neuropeptides. Regulation Hypothalamus. Hypophysis. Epiphysis. Urophysis Luteinizing hormone releasing hormone (LHRH) Male Male rat brain Medial preoptic area Microscopy, Electron Neurons - ultrastructure Preoptic Area - metabolism Preoptic Area - ultrastructure Rats Rats, Inbred F344 Synapse Synapses - ultrastructure Ultrastructure Vertebrates: endocrinology |
| title | Synaptology of luteinizing hormone-releasing hormone neurons in rat preoptic area |
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