Evidence for Endothelium-Derived Relaxing Factor in Cultured Cells

Intracellular cyclic GMP concentration was used as a biochemical indicator of endothelium-dependent and organonitrate-induced responses to these vasodilators in cultured porcine aortic smooth muscle and endothelial cells. Sodium nitroprusside (10M) caused a rapid increase in cyclic GMP levels in con...

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Veröffentlicht in:	Hypertension (Dallas, Tex. 1979) Tex. 1979), 1985-09, Vol.7 (5), p.804-807
Hauptverfasser:	LOEB, ALEX L, OWENS, GARY K, PEACH, MICHAEL J
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Aorta, Thoracic - cytology Arterial hypertension. Arterial hypotension Biological and medical sciences Blood and lymphatic vessels Cardiology. Vascular system Cells, Cultured Cyclic GMP - analysis Experimental diseases Medical sciences Methacholine Compounds - pharmacology Muscle, Smooth, Vascular - cytology Nitric Oxide Nitroprusside - pharmacology Swine Vasodilator Agents - physiology
Online-Zugang:	Volltext
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