Differential response of lymphocytes to free and Sepharose-linked anti-immunoglobulin during different phases of the cell cycle

During proliferation induced by anti-immunoglobulins, B lymphocytes undergo cell volume increases prior to onset of DNA synthesis. Although both Sepharose-linked and free anti-immunoglobulin evoked essentially identical increases in cell volume, the Sepharose-linked antibody induced a significantly...

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Veröffentlicht in:	Experimental cell research 1985-07, Vol.159 (1), p.257-260
Hauptverfasser:	Ramanadham, Madduri, Kern, Milton
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antibodies, Anti-Idiotypic B-Lymphocytes - cytology Biological and medical sciences Cell Cycle Cells, Cultured DNA - biosynthesis Fundamental and applied biological sciences. Psychology Fundamental immunology Immunobiology Immunoglobulin G Immunological reactions in vitro Lymphoblastic transformation (stimulation by antigen, mitogen, mixed lymphocyte reactions) Rabbits
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