Lymphocyte enhancer-binding factor 1: an essential factor in odontoblastic differentiation of dental pulp cells enzymatically isolated from rat incisors

Lymphocyte enhancer-binding factor 1 (Lef1), a HMG-domain protein, is thought to play important roles in inductive tissue interaction during tooth development. Lef1 knockdown in mice causes arrest at the bud stage in tooth development. As this gene participates in the regulation of a large and diver...

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Veröffentlicht in:	Journal of bone and mineral metabolism 2010-11, Vol.28 (6), p.650-658
Hauptverfasser:	Yokose, Satoshi, Naka, Takahiro
Format:	Artikel
Sprache:	eng
Schlagworte:	Alkaline Phosphatase - genetics Alkaline Phosphatase - metabolism Animals Biological and medical sciences Cell Differentiation Cells, Cultured Dental Pulp - cytology Dental Pulp - metabolism Dental pulp cells Dentinogenesis Diseases of the osteoarticular system Extracellular Matrix Proteins - genetics Extracellular Matrix Proteins - metabolism Female Gene Expression Regulation Gene Silencing Genes, Reporter Incisor Lef1 Lymphoid Enhancer-Binding Factor 1 - biosynthesis Lymphoid Enhancer-Binding Factor 1 - genetics Lymphoid Enhancer-Binding Factor 1 - physiology Medical sciences Medicine Medicine & Public Health Metabolic Diseases Odontoblast differentiation Odontoblasts - cytology Odontoblasts - metabolism Original Article Orthopedics Osteocalcin - genetics Osteocalcin - metabolism Phosphoproteins - genetics Phosphoproteins - metabolism Proteins Rats Rats, Sprague-Dawley RNA, Messenger - metabolism RNA, Small Interfering Sialoglycoproteins - genetics Sialoglycoproteins - metabolism Tooth Calcification
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