Impact of Tumor Biology, Particularly Triple-negative Status, on Response to Pre-operative Sequential, Dose-dense Epirubicin, Cyclophosphamide Followed by Docetaxel in Breast Cancer

The central objective of this study was to determine the predictive impact of several established tumor biological factors (PgR, ER, HER2 and Ki-67) on response to pre-operative chemotherapy in primary breast cancer. 59 primary M0 breast cancer patients received pre-operative sequential dose-dense e...

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Veröffentlicht in:	Anticancer research 2010-10, Vol.30 (10), p.4251-4259
Hauptverfasser:	WARM, M, KATES, R, GROSSE-ONNEBRINK, Em, STOFF-KHALILI, M, HOOPMANN, M, MALLMANN, P, THOMAS, A, HARBECK, N
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Aged Antineoplastic Combined Chemotherapy Protocols - administration & dosage Antineoplastic Combined Chemotherapy Protocols - adverse effects Biological and medical sciences Breast Neoplasms - drug therapy Breast Neoplasms - metabolism Breast Neoplasms - pathology Breast Neoplasms - surgery Cyclophosphamide - administration & dosage Dose-Response Relationship, Drug Drug Administration Schedule Epirubicin - administration & dosage Female Gynecology. Andrology. Obstetrics Humans Mammary gland diseases Medical sciences Middle Aged Multivariate Analysis Neoadjuvant Therapy Prospective Studies Receptor, ErbB-2 - biosynthesis Receptors, Estrogen - biosynthesis Receptors, Progesterone - biosynthesis Taxoids - administration & dosage Tumors Young Adult
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