Cellular blue nevus (CBN) lymph node metastases of the neck with no primary skin lesion: A case report and review of literature
Summary A case of cervical lymph node infiltration by a benign cellular blue nevus (CBN) and a 27-year disease history is presented. Dermal dendritic melanocytes and pigmented spindle cells presented no histological evidence of malignancy (CD34−, desmin−, PanCy−, HMB-45+, anti-S-100+, Bcl-2+, MART-1...
Gespeichert in:
| Veröffentlicht in: | Journal of cranio-maxillo-facial surgery 2010-12, Vol.38 (8), p.601-604 |
|---|---|
| Hauptverfasser: | , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 604 |
|---|---|
| container_issue | 8 |
| container_start_page | 601 |
| container_title | Journal of cranio-maxillo-facial surgery |
| container_volume | 38 |
| creator | Scheller, Konstanze, MD, DMD Scheller, Christian, MD Becker, Susann, MD Holzhausen, Hans-Jürgen, MD, PhD Schubert, Johannes, MD, DMD, PhD |
| description | Summary A case of cervical lymph node infiltration by a benign cellular blue nevus (CBN) and a 27-year disease history is presented. Dermal dendritic melanocytes and pigmented spindle cells presented no histological evidence of malignancy (CD34−, desmin−, PanCy−, HMB-45+, anti-S-100+, Bcl-2+, MART-1+, focally expression of melan A, 1% Ki-67+ of the tumour cell nucleoli). The differentiation of the benign blue nevus (BN) from a malignant blue nevus (MBN) and a malignant melanoma (MM) is still a challenge. Because of the malignant transformation potential of 5.2–6.3% a histological examination and a conservative surgical approach with close follow up are mandatory. |
| doi_str_mv | 10.1016/j.jcms.2010.01.008 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_762684692</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>S101051821000020X</els_id><sourcerecordid>762684692</sourcerecordid><originalsourceid>FETCH-LOGICAL-c440t-2277d7453c418b321534fcc031861b4957d6fa52b444bec6463f5be99125a8103</originalsourceid><addsrcrecordid>eNp9kt2L1DAQwIso3of-Az5IXsTzoWsmTdP2EOFc_IJDH1TwLaTplMtumq6Z9o598l83ZVcFH4RAhuQ3k8yPybInwFfAQb3crDZ2oJXg6YDDivP6XnYKdVXnEqC5n-J0k5dQi5PsjGjDOVe8bh5mJ4ILUaiqOs1-rtH72ZvIWj8jC3g7E7tYv_n0gvn9sLthYeyQDTgZSguJjT2bbhbQbtmdmxaA7aIbTNwz2rrAPJIbwyW7YjYlsIi7MU7MhC6Ftw7vlgreTRjNNEd8lD3ojSd8fNzPs2_v3n5df8ivP7__uL66zq2UfMqFqKqukmVhJdRtIaAsZG8tL6BW0MqmrDrVm1K0UsoWrZKq6MsWmwZEaWrgxXn2_FB3F8cfM9KkB0c29W4CjjPpSglVS9WIRIoDaeNIFLHXx_Y0cL141xu9eNeLd81BJ-8p6emx_NwO2P1J-S06Ac-OgCFrfB9NsI7-coWU0JRN4l4dOEwykq6oyToMFjsX0U66G93___H6n3TrXXDpxS3ukTbjHEPSrEGT0Fx_WSZkGRBIs8EF_178AoiJtN8</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>762684692</pqid></control><display><type>article</type><title>Cellular blue nevus (CBN) lymph node metastases of the neck with no primary skin lesion: A case report and review of literature</title><source>MEDLINE</source><source>Access via ScienceDirect (Elsevier)</source><creator>Scheller, Konstanze, MD, DMD ; Scheller, Christian, MD ; Becker, Susann, MD ; Holzhausen, Hans-Jürgen, MD, PhD ; Schubert, Johannes, MD, DMD, PhD</creator><creatorcontrib>Scheller, Konstanze, MD, DMD ; Scheller, Christian, MD ; Becker, Susann, MD ; Holzhausen, Hans-Jürgen, MD, PhD ; Schubert, Johannes, MD, DMD, PhD</creatorcontrib><description>Summary A case of cervical lymph node infiltration by a benign cellular blue nevus (CBN) and a 27-year disease history is presented. Dermal dendritic melanocytes and pigmented spindle cells presented no histological evidence of malignancy (CD34−, desmin−, PanCy−, HMB-45+, anti-S-100+, Bcl-2+, MART-1+, focally expression of melan A, 1% Ki-67+ of the tumour cell nucleoli). The differentiation of the benign blue nevus (BN) from a malignant blue nevus (MBN) and a malignant melanoma (MM) is still a challenge. Because of the malignant transformation potential of 5.2–6.3% a histological examination and a conservative surgical approach with close follow up are mandatory.</description><identifier>ISSN: 1010-5182</identifier><identifier>EISSN: 1878-4119</identifier><identifier>DOI: 10.1016/j.jcms.2010.01.008</identifier><identifier>PMID: 20223677</identifier><identifier>CODEN: JCMSET</identifier><language>eng</language><publisher>Kidlington: Elsevier Ltd</publisher><subject>Biological and medical sciences ; cellular blue nevus (CBN) lymph node metastases ; Dentistry ; Dermatology ; Diagnosis, Differential ; Hematologic and hematopoietic diseases ; Humans ; Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis ; Lymph Nodes - pathology ; Lymph Nodes - surgery ; Lymphatic Metastasis ; Male ; Medical sciences ; Melanoma - pathology ; Middle Aged ; Neck ; Nevus, Blue - pathology ; Nevus, Blue - surgery ; no malignant transformation ; no primary skin-lesion ; Otorhinolaryngology. Stomatology ; Skin Neoplasms - pathology ; Skin Neoplasms - surgery ; Surgery ; Treatment Outcome ; Tumors of the skin and soft tissue. Premalignant lesions</subject><ispartof>Journal of cranio-maxillo-facial surgery, 2010-12, Vol.38 (8), p.601-604</ispartof><rights>European Association for Cranio-Maxillo-Facial Surgery</rights><rights>2010 European Association for Cranio-Maxillo-Facial Surgery</rights><rights>2015 INIST-CNRS</rights><rights>Copyright © 2010 European Association for Cranio-Maxillo-Facial Surgery. Published by Elsevier Ltd. All rights reserved.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c440t-2277d7453c418b321534fcc031861b4957d6fa52b444bec6463f5be99125a8103</citedby><cites>FETCH-LOGICAL-c440t-2277d7453c418b321534fcc031861b4957d6fa52b444bec6463f5be99125a8103</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/j.jcms.2010.01.008$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,780,784,3550,27924,27925,45995</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=23441959$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/20223677$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Scheller, Konstanze, MD, DMD</creatorcontrib><creatorcontrib>Scheller, Christian, MD</creatorcontrib><creatorcontrib>Becker, Susann, MD</creatorcontrib><creatorcontrib>Holzhausen, Hans-Jürgen, MD, PhD</creatorcontrib><creatorcontrib>Schubert, Johannes, MD, DMD, PhD</creatorcontrib><title>Cellular blue nevus (CBN) lymph node metastases of the neck with no primary skin lesion: A case report and review of literature</title><title>Journal of cranio-maxillo-facial surgery</title><addtitle>J Craniomaxillofac Surg</addtitle><description>Summary A case of cervical lymph node infiltration by a benign cellular blue nevus (CBN) and a 27-year disease history is presented. Dermal dendritic melanocytes and pigmented spindle cells presented no histological evidence of malignancy (CD34−, desmin−, PanCy−, HMB-45+, anti-S-100+, Bcl-2+, MART-1+, focally expression of melan A, 1% Ki-67+ of the tumour cell nucleoli). The differentiation of the benign blue nevus (BN) from a malignant blue nevus (MBN) and a malignant melanoma (MM) is still a challenge. Because of the malignant transformation potential of 5.2–6.3% a histological examination and a conservative surgical approach with close follow up are mandatory.</description><subject>Biological and medical sciences</subject><subject>cellular blue nevus (CBN) lymph node metastases</subject><subject>Dentistry</subject><subject>Dermatology</subject><subject>Diagnosis, Differential</subject><subject>Hematologic and hematopoietic diseases</subject><subject>Humans</subject><subject>Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis</subject><subject>Lymph Nodes - pathology</subject><subject>Lymph Nodes - surgery</subject><subject>Lymphatic Metastasis</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Melanoma - pathology</subject><subject>Middle Aged</subject><subject>Neck</subject><subject>Nevus, Blue - pathology</subject><subject>Nevus, Blue - surgery</subject><subject>no malignant transformation</subject><subject>no primary skin-lesion</subject><subject>Otorhinolaryngology. Stomatology</subject><subject>Skin Neoplasms - pathology</subject><subject>Skin Neoplasms - surgery</subject><subject>Surgery</subject><subject>Treatment Outcome</subject><subject>Tumors of the skin and soft tissue. Premalignant lesions</subject><issn>1010-5182</issn><issn>1878-4119</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2010</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kt2L1DAQwIso3of-Az5IXsTzoWsmTdP2EOFc_IJDH1TwLaTplMtumq6Z9o598l83ZVcFH4RAhuQ3k8yPybInwFfAQb3crDZ2oJXg6YDDivP6XnYKdVXnEqC5n-J0k5dQi5PsjGjDOVe8bh5mJ4ILUaiqOs1-rtH72ZvIWj8jC3g7E7tYv_n0gvn9sLthYeyQDTgZSguJjT2bbhbQbtmdmxaA7aIbTNwz2rrAPJIbwyW7YjYlsIi7MU7MhC6Ftw7vlgreTRjNNEd8lD3ojSd8fNzPs2_v3n5df8ivP7__uL66zq2UfMqFqKqukmVhJdRtIaAsZG8tL6BW0MqmrDrVm1K0UsoWrZKq6MsWmwZEaWrgxXn2_FB3F8cfM9KkB0c29W4CjjPpSglVS9WIRIoDaeNIFLHXx_Y0cL141xu9eNeLd81BJ-8p6emx_NwO2P1J-S06Ac-OgCFrfB9NsI7-coWU0JRN4l4dOEwykq6oyToMFjsX0U66G93___H6n3TrXXDpxS3ukTbjHEPSrEGT0Fx_WSZkGRBIs8EF_178AoiJtN8</recordid><startdate>20101201</startdate><enddate>20101201</enddate><creator>Scheller, Konstanze, MD, DMD</creator><creator>Scheller, Christian, MD</creator><creator>Becker, Susann, MD</creator><creator>Holzhausen, Hans-Jürgen, MD, PhD</creator><creator>Schubert, Johannes, MD, DMD, PhD</creator><general>Elsevier Ltd</general><general>Elsevier</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20101201</creationdate><title>Cellular blue nevus (CBN) lymph node metastases of the neck with no primary skin lesion: A case report and review of literature</title><author>Scheller, Konstanze, MD, DMD ; Scheller, Christian, MD ; Becker, Susann, MD ; Holzhausen, Hans-Jürgen, MD, PhD ; Schubert, Johannes, MD, DMD, PhD</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c440t-2277d7453c418b321534fcc031861b4957d6fa52b444bec6463f5be99125a8103</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2010</creationdate><topic>Biological and medical sciences</topic><topic>cellular blue nevus (CBN) lymph node metastases</topic><topic>Dentistry</topic><topic>Dermatology</topic><topic>Diagnosis, Differential</topic><topic>Hematologic and hematopoietic diseases</topic><topic>Humans</topic><topic>Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis</topic><topic>Lymph Nodes - pathology</topic><topic>Lymph Nodes - surgery</topic><topic>Lymphatic Metastasis</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Melanoma - pathology</topic><topic>Middle Aged</topic><topic>Neck</topic><topic>Nevus, Blue - pathology</topic><topic>Nevus, Blue - surgery</topic><topic>no malignant transformation</topic><topic>no primary skin-lesion</topic><topic>Otorhinolaryngology. Stomatology</topic><topic>Skin Neoplasms - pathology</topic><topic>Skin Neoplasms - surgery</topic><topic>Surgery</topic><topic>Treatment Outcome</topic><topic>Tumors of the skin and soft tissue. Premalignant lesions</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Scheller, Konstanze, MD, DMD</creatorcontrib><creatorcontrib>Scheller, Christian, MD</creatorcontrib><creatorcontrib>Becker, Susann, MD</creatorcontrib><creatorcontrib>Holzhausen, Hans-Jürgen, MD, PhD</creatorcontrib><creatorcontrib>Schubert, Johannes, MD, DMD, PhD</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of cranio-maxillo-facial surgery</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Scheller, Konstanze, MD, DMD</au><au>Scheller, Christian, MD</au><au>Becker, Susann, MD</au><au>Holzhausen, Hans-Jürgen, MD, PhD</au><au>Schubert, Johannes, MD, DMD, PhD</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Cellular blue nevus (CBN) lymph node metastases of the neck with no primary skin lesion: A case report and review of literature</atitle><jtitle>Journal of cranio-maxillo-facial surgery</jtitle><addtitle>J Craniomaxillofac Surg</addtitle><date>2010-12-01</date><risdate>2010</risdate><volume>38</volume><issue>8</issue><spage>601</spage><epage>604</epage><pages>601-604</pages><issn>1010-5182</issn><eissn>1878-4119</eissn><coden>JCMSET</coden><abstract>Summary A case of cervical lymph node infiltration by a benign cellular blue nevus (CBN) and a 27-year disease history is presented. Dermal dendritic melanocytes and pigmented spindle cells presented no histological evidence of malignancy (CD34−, desmin−, PanCy−, HMB-45+, anti-S-100+, Bcl-2+, MART-1+, focally expression of melan A, 1% Ki-67+ of the tumour cell nucleoli). The differentiation of the benign blue nevus (BN) from a malignant blue nevus (MBN) and a malignant melanoma (MM) is still a challenge. Because of the malignant transformation potential of 5.2–6.3% a histological examination and a conservative surgical approach with close follow up are mandatory.</abstract><cop>Kidlington</cop><pub>Elsevier Ltd</pub><pmid>20223677</pmid><doi>10.1016/j.jcms.2010.01.008</doi><tpages>4</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1010-5182 |
| ispartof | Journal of cranio-maxillo-facial surgery, 2010-12, Vol.38 (8), p.601-604 |
| issn | 1010-5182 1878-4119 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_762684692 |
| source | MEDLINE; Access via ScienceDirect (Elsevier) |
| subjects | Biological and medical sciences cellular blue nevus (CBN) lymph node metastases Dentistry Dermatology Diagnosis, Differential Hematologic and hematopoietic diseases Humans Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis Lymph Nodes - pathology Lymph Nodes - surgery Lymphatic Metastasis Male Medical sciences Melanoma - pathology Middle Aged Neck Nevus, Blue - pathology Nevus, Blue - surgery no malignant transformation no primary skin-lesion Otorhinolaryngology. Stomatology Skin Neoplasms - pathology Skin Neoplasms - surgery Surgery Treatment Outcome Tumors of the skin and soft tissue. Premalignant lesions |
| title | Cellular blue nevus (CBN) lymph node metastases of the neck with no primary skin lesion: A case report and review of literature |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-21T16%3A03%3A44IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Cellular%20blue%20nevus%20(CBN)%20lymph%20node%20metastases%20of%20the%20neck%20with%20no%20primary%20skin%20lesion:%20A%20case%20report%20and%20review%20of%20literature&rft.jtitle=Journal%20of%20cranio-maxillo-facial%20surgery&rft.au=Scheller,%20Konstanze,%20MD,%20DMD&rft.date=2010-12-01&rft.volume=38&rft.issue=8&rft.spage=601&rft.epage=604&rft.pages=601-604&rft.issn=1010-5182&rft.eissn=1878-4119&rft.coden=JCMSET&rft_id=info:doi/10.1016/j.jcms.2010.01.008&rft_dat=%3Cproquest_cross%3E762684692%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=762684692&rft_id=info:pmid/20223677&rft_els_id=S101051821000020X&rfr_iscdi=true |