The wily ways of a parasite: induction of actin assembly by Listeria

The intracellular pathogen Listeria has a spectacular mode of transport within and between host cells. By inducing host cell actin to assemble from its surface, the bacterium forms a tail composed of many short, crossbridged actin filaments. With this tail Listeria is propelled across the cytoplasm...

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Veröffentlicht in:Trends in Microbiology 1993-04, Vol.1 (1), p.25-31
Hauptverfasser: Tilney, Lewis G., Tilney, Mary S.
Format: Artikel
Sprache:eng
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Zusammenfassung:The intracellular pathogen Listeria has a spectacular mode of transport within and between host cells. By inducing host cell actin to assemble from its surface, the bacterium forms a tail composed of many short, crossbridged actin filaments. With this tail Listeria is propelled across the cytoplasm like a comet streaking across the sky. Here we discuss the antics of Listeria and some of the bacterial genes instrumental in maintaining it in the host.
ISSN:0966-842X
1878-4380
DOI:10.1016/0966-842X(93)90021-I