Comparison of Inhibitory and Binding Characteristics of an Antibody Causing Acquired von Willebrand Syndrome: An Assay for von Willebrand Factor Binding by Antibody

An acquired inhibitor of von Willebrand factor (vWF) activity occurring in a patient with benign gammopathy and von Willebrand syndrome (vWS) has been partially characterized. The inhibitor-induced syndrome resulted in low to undetectable plasma levels of vWF/ristocetin, vWF/botrocetin, FVIIIR:Ag, a...

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Veröffentlicht in:	Blood 1985-09, Vol.66 (3), p.562-569
Hauptverfasser:	Fricke, William A., Brinkhous, K.M., Garris, J.B., Roberts, Harold R.
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Binding Sites, Antibody Binding, Competitive Biological and medical sciences Bleeding Time Blood Coagulation Factors - immunology Blood Coagulation Tests Blood Platelets - analysis Factor VIII - administration & dosage Hematologic and hematopoietic diseases Humans Infusions, Parenteral Isoantibodies - administration & dosage Isoantibodies - physiology Male Medical sciences Platelet diseases and coagulopathies Syndrome von Willebrand Diseases - blood von Willebrand Diseases - etiology von Willebrand Diseases - immunology von Willebrand Factor - immunology von Willebrand Factor - metabolism
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