The effect of different hyperglucagonemic states on monooxygenase activities and isozymic pattern of cytochrome P-450 in mouse

The continuous infusion of a low dose of glucagon (35 micrograms/kg/d, for 5 d) constitutes, in view of glucose-6-phosphatase and phosphoenolpyruvate carboxykinase activities, a reliable experimental model of hyperglucagonemia. By conjunction of monooxygenase assays and immunoquantitation of specifi...

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Veröffentlicht in:	Bioscience reports 1985-04, Vol.5 (4), p.335-341
Hauptverfasser:	Rouer, E, Beaune, P, Augereau, C, Leroux, J P
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cytochrome P-450 Enzyme System - metabolism Diabetes Mellitus, Experimental - metabolism Fasting Glucagon - blood Glucagon - pharmacology Isoenzymes - metabolism Male Mice Mice, Inbred C57BL Microsomes, Liver - drug effects Microsomes, Liver - metabolism Oxygenases - metabolism
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