Downregulation of serotonin receptor subtypes by nortriptyline and adinazolam in major depressive disorder : neuroendocrine and platelet markers

Neuroendocrine and platelet markers of serotonin (5-hydroxytryptamine, 5-HT) receptor functioning are useful tools for studying the downregulation of 5-HT receptors, a leading hypothesis for the mechanism of action of antidepressant drugs. The 5-HT releaser fenfluramine raises body temperature as we...

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Veröffentlicht in:	Clinical neuropharmacology 1993, Vol.16, p.S19-S31
Hauptverfasser:	STAHL, S. M, HAUGER, R. L, RAUSCH, J. L, FLEISHAKER, J. C, HUBBELL-ALBERTS, E
Format:	Artikel
Sprache:	eng
Schlagworte:	Anti-Anxiety Agents Antidepressive Agents - therapeutic use Benzodiazepines - therapeutic use Biological and medical sciences Biomarkers - analysis Biomarkers - blood Blood Platelets - cytology Blood Platelets - drug effects Body Temperature - drug effects Cell Size - drug effects Depressive Disorder - drug therapy Depressive Disorder - physiopathology Double-Blind Method Down-Regulation - drug effects Fenfluramine - therapeutic use Humans Medical sciences Neuropharmacology Neurosecretory Systems - drug effects Neurosecretory Systems - physiology Nortriptyline - therapeutic use Pharmacology. Drug treatments Psychoanaleptics: cns stimulant, antidepressant agent, nootropic agent, mood stabilizer..., (alzheimer disease) Psychology. Psychoanalysis. Psychiatry Psychopharmacology Receptors, Serotonin - classification Receptors, Serotonin - drug effects Receptors, Serotonin - physiology
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