Pituitary apoplexy in an adrenocorticotropin-producing pituitary macroadenoma
Adrenocorticotropin (ACTH) producing macroadenomas and pituitary apoplexy are unusual in Cushing’ s disease. A 20-year-old man who had been diagnosed Cushing’ s disease 2 months ago, presented with sudden headache, nausea, and vomiting. His serum cortisol level was 0.4 μg/dl and ACTH level was 23.9 ...
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| Veröffentlicht in: | Endocrine 2010-10, Vol.38 (2), p.143-146 |
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| container_title | Endocrine |
| container_volume | 38 |
| creator | Sahin, Serap Baydur Cetinkalp, S. Erdogan, M. Cavdar, U. Duygulu, G. Saygili, F. Yilmaz, C. Ozgen, A. G. |
| description | Adrenocorticotropin (ACTH) producing macroadenomas and pituitary apoplexy are unusual in Cushing’ s disease. A 20-year-old man who had been diagnosed Cushing’ s disease 2 months ago, presented with sudden headache, nausea, and vomiting. His serum cortisol level was 0.4 μg/dl and ACTH level was 23.9 pg/ml. Magnetic resonance imaging of the pituitary gland disclosed a hemorrhage in the pituitary macroadenoma (22 × 19 mm). He was treated with IV methylprednisolone immediately and then the symptoms were relieved within the first day of the treatment. The hemorrhagic lesion was resected by transsphenoidal surgery successfully. Impaired secretion of pituitary hormones may be seen after the pituitary apoplexy. We communicate a case with pituitary apoplexy of an ACTH secreting pituitary macroadenoma, causing acute glucocorticoid insufficiency. |
| doi_str_mv | 10.1007/s12020-010-9367-8 |
| format | Article |
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We communicate a case with pituitary apoplexy of an ACTH secreting pituitary macroadenoma, causing acute glucocorticoid insufficiency.</description><identifier>ISSN: 1355-008X</identifier><identifier>EISSN: 1559-0100</identifier><identifier>DOI: 10.1007/s12020-010-9367-8</identifier><identifier>PMID: 21046475</identifier><language>eng</language><publisher>Boston: Springer US</publisher><subject>ACTH-Secreting Pituitary Adenoma - complications ; ACTH-Secreting Pituitary Adenoma - pathology ; ACTH-Secreting Pituitary Adenoma - surgery ; Acute Disease ; Adenoma - complications ; Adenoma - pathology ; Adenoma - surgery ; Case Report ; Diabetes ; Endocrinology ; Humanities and Social Sciences ; Humans ; Internal Medicine ; Magnetic Resonance Imaging ; Male ; Medicine ; Medicine & Public Health ; multidisciplinary ; Pituitary ACTH Hypersecretion - etiology ; Pituitary ACTH Hypersecretion - pathology ; Pituitary ACTH Hypersecretion - surgery ; Pituitary Apoplexy - etiology ; Pituitary Apoplexy - pathology ; Pituitary Apoplexy - surgery ; Science ; Young Adult</subject><ispartof>Endocrine, 2010-10, Vol.38 (2), p.143-146</ispartof><rights>Springer Science+Business Media, LLC 2010</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c343t-639eeca2197e3b1ab92cea8bb84d98ddfead2a5d3c9fdaeb8108c7fac1f59b773</citedby><cites>FETCH-LOGICAL-c343t-639eeca2197e3b1ab92cea8bb84d98ddfead2a5d3c9fdaeb8108c7fac1f59b773</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s12020-010-9367-8$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s12020-010-9367-8$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>314,780,784,27924,27925,41488,42557,51319</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/21046475$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Sahin, Serap Baydur</creatorcontrib><creatorcontrib>Cetinkalp, S.</creatorcontrib><creatorcontrib>Erdogan, M.</creatorcontrib><creatorcontrib>Cavdar, U.</creatorcontrib><creatorcontrib>Duygulu, G.</creatorcontrib><creatorcontrib>Saygili, F.</creatorcontrib><creatorcontrib>Yilmaz, C.</creatorcontrib><creatorcontrib>Ozgen, A. G.</creatorcontrib><title>Pituitary apoplexy in an adrenocorticotropin-producing pituitary macroadenoma</title><title>Endocrine</title><addtitle>Endocr</addtitle><addtitle>Endocrine</addtitle><description>Adrenocorticotropin (ACTH) producing macroadenomas and pituitary apoplexy are unusual in Cushing’ s disease. A 20-year-old man who had been diagnosed Cushing’ s disease 2 months ago, presented with sudden headache, nausea, and vomiting. His serum cortisol level was 0.4 μg/dl and ACTH level was 23.9 pg/ml. Magnetic resonance imaging of the pituitary gland disclosed a hemorrhage in the pituitary macroadenoma (22 × 19 mm). He was treated with IV methylprednisolone immediately and then the symptoms were relieved within the first day of the treatment. The hemorrhagic lesion was resected by transsphenoidal surgery successfully. Impaired secretion of pituitary hormones may be seen after the pituitary apoplexy. We communicate a case with pituitary apoplexy of an ACTH secreting pituitary macroadenoma, causing acute glucocorticoid insufficiency.</description><subject>ACTH-Secreting Pituitary Adenoma - complications</subject><subject>ACTH-Secreting Pituitary Adenoma - pathology</subject><subject>ACTH-Secreting Pituitary Adenoma - surgery</subject><subject>Acute Disease</subject><subject>Adenoma - complications</subject><subject>Adenoma - pathology</subject><subject>Adenoma - surgery</subject><subject>Case Report</subject><subject>Diabetes</subject><subject>Endocrinology</subject><subject>Humanities and Social Sciences</subject><subject>Humans</subject><subject>Internal Medicine</subject><subject>Magnetic Resonance Imaging</subject><subject>Male</subject><subject>Medicine</subject><subject>Medicine & Public Health</subject><subject>multidisciplinary</subject><subject>Pituitary ACTH Hypersecretion - etiology</subject><subject>Pituitary ACTH Hypersecretion - pathology</subject><subject>Pituitary ACTH Hypersecretion - surgery</subject><subject>Pituitary Apoplexy - etiology</subject><subject>Pituitary Apoplexy - pathology</subject><subject>Pituitary Apoplexy - surgery</subject><subject>Science</subject><subject>Young Adult</subject><issn>1355-008X</issn><issn>1559-0100</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2010</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kM1KxDAUhYMozjj6AG5kdq6iN0nbJEsZ_ANFFwruQpqkQ4e2qUkLztuboeMshcANud85nByELgncEAB-GwkFChgIYMkKjsURmpM8l7sXOE53lucYQHzN0FmMGwBKacFP0YwSyIqM53P0-l4PYz3osF3q3veN-9ku626p07HBdd74MNTGD8H3dYf74O1o6m697A-yVpvgtU1sq8_RSaWb6C72c4E-H-4_Vk_45e3xeXX3gg3L2IALJp0zmhLJHSuJLiU1TouyFJmVwtrKaUt1bpmRldWuFASE4ZU2pMplyTlboOvJNwX6Hl0cVFtH45pGd86PUfGCZlwKYIkkE5lCxhhcpfpQtym3IqB2JaqpRJUqU7sSlUiaq737WLbOHhR_rSWATkBMq27tgtr4MXTpx_-4_gIsE4AS</recordid><startdate>20101001</startdate><enddate>20101001</enddate><creator>Sahin, Serap Baydur</creator><creator>Cetinkalp, S.</creator><creator>Erdogan, M.</creator><creator>Cavdar, U.</creator><creator>Duygulu, G.</creator><creator>Saygili, F.</creator><creator>Yilmaz, C.</creator><creator>Ozgen, A. 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| subjects | ACTH-Secreting Pituitary Adenoma - complications ACTH-Secreting Pituitary Adenoma - pathology ACTH-Secreting Pituitary Adenoma - surgery Acute Disease Adenoma - complications Adenoma - pathology Adenoma - surgery Case Report Diabetes Endocrinology Humanities and Social Sciences Humans Internal Medicine Magnetic Resonance Imaging Male Medicine Medicine & Public Health multidisciplinary Pituitary ACTH Hypersecretion - etiology Pituitary ACTH Hypersecretion - pathology Pituitary ACTH Hypersecretion - surgery Pituitary Apoplexy - etiology Pituitary Apoplexy - pathology Pituitary Apoplexy - surgery Science Young Adult |
| title | Pituitary apoplexy in an adrenocorticotropin-producing pituitary macroadenoma |
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