Aspirin Desensitization/Challenge in 3 Patients With Unstable Angina
Aspirin sensitivity is relatively frequent and can be a major problem in patients who need percutaneous coronary intervention and stenting with subsequent dual antiplatelet therapy. Desensitization is often the therapy in these patients, but this can prolong the time to revascularization significant...
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| Veröffentlicht in: | The American journal of the medical sciences 2010-11, Vol.340 (5), p.418-420 |
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| container_end_page | 420 |
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| container_issue | 5 |
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| container_title | The American journal of the medical sciences |
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| creator | Ortega-Loayza, Alex G. Raza, Syed Minisi, Anthony J. Topaz, On Jovin, Ion S. Heller, Andrew |
| description | Aspirin sensitivity is relatively frequent and can be a major problem in patients who need percutaneous coronary intervention and stenting with subsequent dual antiplatelet therapy. Desensitization is often the therapy in these patients, but this can prolong the time to revascularization significantly. Rapid oral aspirin desensitization protocols have been described since 2000. However, data are lacking on the optimal strategy for aspirin desensitization and determining which patients are mostly benefited from this desensitization. The authors describe the use of a Wong-modified protocol in 3 patients who had known aspirin sensitivity and who had unstable angina and an indication for percutaneous coronary intervention. |
| doi_str_mv | 10.1097/MAJ.0b013e3181eecfc7 |
| format | Article |
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Desensitization is often the therapy in these patients, but this can prolong the time to revascularization significantly. Rapid oral aspirin desensitization protocols have been described since 2000. However, data are lacking on the optimal strategy for aspirin desensitization and determining which patients are mostly benefited from this desensitization. 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Desensitization is often the therapy in these patients, but this can prolong the time to revascularization significantly. Rapid oral aspirin desensitization protocols have been described since 2000. However, data are lacking on the optimal strategy for aspirin desensitization and determining which patients are mostly benefited from this desensitization. The authors describe the use of a Wong-modified protocol in 3 patients who had known aspirin sensitivity and who had unstable angina and an indication for percutaneous coronary intervention.</description><subject>Acute coronary syndrome</subject><subject>Angina, Unstable - drug therapy</subject><subject>Aspirin - immunology</subject><subject>Aspirin - therapeutic use</subject><subject>Aspirin allergy</subject><subject>Biological and medical sciences</subject><subject>Cardiology. Vascular system</subject><subject>Coronary heart disease</subject><subject>Desensitization</subject><subject>Desensitization, Immunologic</subject><subject>General aspects</subject><subject>Heart</subject><subject>Humans</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Platelet Aggregation Inhibitors - immunology</subject><subject>Platelet Aggregation Inhibitors - therapeutic use</subject><subject>Radiotherapy. Instrumental treatment. Physiotherapy. Reeducation. Rehabilitation, orthophony, crenotherapy. 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| subjects | Acute coronary syndrome Angina, Unstable - drug therapy Aspirin - immunology Aspirin - therapeutic use Aspirin allergy Biological and medical sciences Cardiology. Vascular system Coronary heart disease Desensitization Desensitization, Immunologic General aspects Heart Humans Male Medical sciences Middle Aged Platelet Aggregation Inhibitors - immunology Platelet Aggregation Inhibitors - therapeutic use Radiotherapy. Instrumental treatment. Physiotherapy. Reeducation. Rehabilitation, orthophony, crenotherapy. Diet therapy and various other treatments (general aspects) Stent |
| title | Aspirin Desensitization/Challenge in 3 Patients With Unstable Angina |
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