Intraepithelial Dendritic Cells and Selective Activation of Th2-Like Lymphocytes in Patients With Atopic Asthma

This study examines the distribution of intraepithelial dendritic cells in eight atopic patients with symptomatic asthma and their ability to induce activation of autologous T lymphocytes in vitro. All subjects were sensitized to Dermatophagoides pteronyssinus. The incubation of asthmatic epithelial...

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Veröffentlicht in:	Chest 1993-04, Vol.103 (4), p.997-1005
Hauptverfasser:	Bellini, Alberto, Vittori, Enza, Marini, Maurizio, Ackerman, Victoria, Mattoli, Sabrina
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Allergic diseases Animals Asthma - complications Asthma - immunology Asthma - pathology Asthma - physiopathology Biological and medical sciences Bronchi - immunology Bronchi - pathology Cells, Cultured Dendritic Cells - immunology Dendritic Cells - pathology Epithelium - immunology Epithelium - pathology Female Forced Expiratory Volume Granulocyte-Macrophage Colony-Stimulating Factor - biosynthesis Humans Hypersensitivity, Immediate - complications Hypersensitivity, Immediate - immunology Immunohistochemistry Immunopathology Interleukin-4 - biosynthesis Interleukin-5 - biosynthesis Lymphocyte Activation Male Medical sciences Mites - immunology Respiratory and ent allergic diseases T-Lymphocytes, Helper-Inducer - immunology
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