Quantitative characterization of cell invasion in vitro: formulation and validation of a mathematical model of the collagen gel invasion assay

An in vitro assay proposed to systematically characterize and compare cell invasion under different conditions is the collagen gel invasion assay where cells, initially seeded onto the surface of a type I collagen gel, penetrate the surface and migrate within the gel over time. Using simplifying ass...

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Veröffentlicht in:	Annals of biomedical engineering 1993-11, Vol.21 (6), p.679-697
Hauptverfasser:	DICKINSON, R. B, MCCARTHY, J. B, TRANQUILLO, R. T
Format:	Artikel
Sprache:	eng
Schlagworte:	Algorithms Animals Biological and medical sciences Cell Movement - physiology Collagen Computer Simulation Fundamental and applied biological sciences. Psychology General aspects Mathematics in biology. Statistical analysis. Models. Metrology. Data processing in biology (general aspects) Models, Biological Neoplasm Invasiveness - physiopathology Surface Properties Tumor Cells, Cultured
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