Mitotic stability and meiotic variability of the (CAG)n repeat in the Huntington disease gene

The gene causing Huntingtons's disease, an autosomal dominantly Inherited, neurodegenerative disorder, has been Identified recently. The corresponding mutation Is Involving an expansion In the number of (CAG)n repeats In the coding region of the Huntington's disease gene on chromosome 4. I...

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Veröffentlicht in:Human molecular genetics 1993-12, Vol.2 (12), p.2063-2067
Hauptverfasser: Zühlke, Christine, Rless, Olaf, Bockel, Barbara, Lange, Herwlg, Thies, Ulrike
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Sprache:eng
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