Changes of Bone Metabolic Markers in Patients with Bone Metastases: Clinical Significance in Assessing Bone Response to Chemotherapy

To determine the changes in bone metabolism in response to combined chemotherapy in patients with bone metastases (BM), we examined osteocalcin (BGP), alkalinephosphatase (ALP), hydroxyproline (HYP), pyridinoline (PYR), and/or deoxypyridinoline (D-PYR) in 25 cancer patients. In patients without BM,...

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Veröffentlicht in:	Internal Medicine 1993, Vol.32(8), pp.611-618
Hauptverfasser:	WADA, Seiki, KATAYAMA, Yasuyuki, YASUTOMO, Yoshirou, KUGAI, Nobuo, NAGATA, Naokazu
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Alkaline Phosphatase - blood Amino Acids - urine Antineoplastic Combined Chemotherapy Protocols - therapeutic use Biological and medical sciences Biomarkers, Tumor - metabolism Bone and Bones - metabolism Bone Neoplasms - drug therapy Bone Neoplasms - metabolism Bone Neoplasms - secondary Bone Resorption - metabolism deoxypyridinoline Female Humans hydroxyproline Hydroxyproline - urine Investigative techniques, diagnostic techniques (general aspects) Male Medical sciences Middle Aged Osteoarticular system. Muscles osteocalcin Osteocalcin - blood Osteogenesis - physiology Pathology. Cytology. Biochemistry. Spectrometry. Miscellaneous investigative techniques Prognosis pyridinoline
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