Alterations in hepatic metabolism of adult male rats following exposure to hydroxyprogesterone during embryonic development

Aim: To investigate the effect of in utero exposure to hydroxyprogesterone (HP) on liver metabolism in adult male albino rats. Methods: Pregnant Wistar strain albino rats were exposed to supra‐normal levels (10 mg/kg and 25 mg/kg) of HP on days 1, 7 and 14 of pregnancy. The male pups were maintained...

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Veröffentlicht in:	Asian journal of andrology 2006-07, Vol.8 (4), p.463-467
Hauptverfasser:	Pushpalatha, T., Reddy, P. Ramachandra, Reddy, P. Sreenivasula
Format:	Artikel
Sprache:	eng
Schlagworte:	17-alpha-Hydroxyprogesterone - administration & dosage 17-alpha-Hydroxyprogesterone - pharmacology Animals antioxidants Catalase - metabolism Embryo, Mammalian - drug effects Embryonic Development Female Glucosephosphate Dehydrogenase - metabolism Glutamate Dehydrogenase - metabolism Glutathione Transferase - metabolism hydroxyprogesterone L-Lactate Dehydrogenase - metabolism Lipid Peroxidation liver Liver - drug effects Liver - embryology Liver - enzymology Liver - metabolism Malate Dehydrogenase - metabolism Male oxidative enzymes Pregnancy Rats Rats, Wistar Succinate Dehydrogenase - metabolism Transaminases - metabolism
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