Nanopore DNA sequencing with MspA

Nanopore sequencing has the potential to become a direct, fast, and inexpensive DNA sequencing technology. The simplest form of nanopore DNA sequencing utilizes the hypothesis that individual nucleotides of single-stranded DNA passing through a nanopore will uniquely modulate an ionic current flowin...

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Veröffentlicht in:	Proceedings of the National Academy of Sciences - PNAS 2010-09, Vol.107 (37), p.16060-16065
Hauptverfasser:	Derrington, Ian M., Butler, Tom Z., Collins, Marcus D., Manrao, Elizabeth, Pavlenok, Mikhail, Niederweis, Michael, Gundlach, Jens H.
Format:	Artikel
Sprache:	eng
Schlagworte:	Bacteria Bacteriology Base Sequence Biological Sciences Conserved sequence Deoxyribonucleic acid DNA DNA - analysis DNA - chemistry DNA - metabolism DNA sequencing Electric potential Histograms Human genome Ion currents Models, Molecular Molecules Mycobacterium smegmatis Mycobacterium smegmatis - chemistry Mycobacterium smegmatis - metabolism Nanostructures - chemistry Nanotechnology Nucleic Acid Conformation Nucleotide sequence Nucleotides Pores Porins Porins - metabolism Porosity Protein Structure, Tertiary Proteins Sequence Analysis, DNA - methods Sequencing Single stranded DNA
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