ΔFosB in the nucleus accumbens is critical for reinforcing effects of sexual reward

Sexual behavior in male rats is rewarding and reinforcing. However, little is known about the specific cellular and molecular mechanisms mediating sexual reward or the reinforcing effects of reward on subsequent expression of sexual behavior. This study tests the hypothesis that ΔFosB, the stably ex...

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Veröffentlicht in:	Genes, brain and behavior brain and behavior, 2010-10, Vol.9 (7), p.831-840
Hauptverfasser:	Pitchers, K. K., Frohmader, K. S., Vialou, V., Mouzon, E., Nestler, E. J., Lehman, M. N., Coolen, L. M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Anterior cingulate area Brain Chemistry - genetics Brain Chemistry - physiology Female Fluorescent Antibody Technique Gene Expression Genetic Vectors Immunoenzyme Techniques learning Male Motivation - genetics Motivation - physiology neuroplasticity Nucleus Accumbens - anatomy & histology Nucleus Accumbens - metabolism Nucleus Accumbens - physiology Proto-Oncogene Proteins c-fos - metabolism Rats Rats, Sprague-Dawley recombinant adeno‐associated viral vector Reinforcement (Psychology) Reward sensitization sexual behavior Sexual Behavior, Animal - physiology
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