Induction of murine interleukin-1 beta expression by water-soluble components from Hericium erinaceum

Aim： To investigate the inductive effect of water extract from Hericiurn erinaceum （WEHE） on interleukin-1β （IL-1β） expression. Methods： A murine macrophage cell-line, RAW 264.7 was stimulated with 1 to 10 mg/L WEHE and inductions of IL-1β protein and its steady state mRNA were examined using a bioa...

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Veröffentlicht in:	Acta pharmacologica Sinica 2006-08, Vol.27 (8), p.1058-1064
Hauptverfasser:	Son, Chang-Gue, Shin, Jang-Woo, Cho, Jung-Hyo, Cho, Chong-Kwan, Yun, Cheol-Heui, Han, Seung-Hyun
Format:	Artikel
Sprache:	eng
Schlagworte:	Agaricales - chemistry Animals beta-Glucans - administration & dosage beta-Glucans - isolation & purification beta-Glucans - pharmacology Biological Products - administration & dosage Biological Products - isolation & purification Biological Products - pharmacology CCAAT-Enhancer-Binding Protein-beta - metabolism Cell Line Dose-Response Relationship, Drug Interleukin-1beta - biosynthesis Interleukin-1beta - genetics Macrophage Activation - drug effects Macrophages - cytology Macrophages - metabolism Mice Mice, Inbred C3H NF-kappa B - metabolism RNA, Messenger - biosynthesis RNA, Messenger - genetics Transcription Factor AP-1 - metabolism 巨噬细胞病理机制白细胞介素-1β 脂多糖
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