Better therapeutics through microarrays

DNA microarrays are an integral part of the process for therapeutic discovery, optimization and clinical validation. At an early stage, investigators use arrays to prioritize a few genes as potential therapeutic targets on the basis of various criteria. Subsequently, gene expression analysis assists...

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Veröffentlicht in:	Nature genetics 2002-12, Vol.32 Suppl (4s), p.547-552
Hauptverfasser:	Gerhold, David L, Jensen, Roderick V, Gullans, Steven R
Format:	Artikel
Sprache:	eng
Schlagworte:	Bioinformatics Biomarkers Clinical trials Computational Biology Deoxyribonucleic acid DNA DNA - genetics DNA - metabolism DNA microarrays Drug Design Drug Evaluation, Preclinical Gene expression Gene Expression - drug effects Gene Expression - genetics Gene Expression Profiling - methods Genetic aspects Genomes Genomics Homeopathy Humans Materia medica and therapeutics Mathematics Medical research Methods Oligonucleotide Array Sequence Analysis - methods Pharmacogenetics - methods Physiological aspects R&D Reproducibility of Results Research & development Sequence Analysis, DNA - methods Statistics as Topic Therapeutics Toxicology Toxicology - methods
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