Cytokine Technology in Basic and Applied Research on the Hematopoietic System
Cytokines are polypeptide molecules important for the regulation and maintenance of immunity and hematopoiesis. Their central role in the control of a number of physiological mechanisms makes them an important area of both basic and applied biomedical research. This review presents an overview of ba...
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| Veröffentlicht in: | Toxicologic pathology 1993-01, Vol.21 (2), p.251-257 |
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| container_title | Toxicologic pathology |
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| creator | House, Robert V. |
| description | Cytokines are polypeptide molecules important for the regulation and maintenance of immunity and hematopoiesis. Their central role in the control of a number of physiological mechanisms makes them an important area of both basic and applied biomedical research. This review presents an overview of basic and applied biology, and introduces the term cytokine technology to denote the use of cytokines as research tools for understanding the cellular and molecular regulation of hematopoiesis. A number of frontier technologies are reviewed, including fusion toxins, fusion proteins, and animal models of cytokine expression and regulation. |
| doi_str_mv | 10.1177/019262339302100218 |
| format | Article |
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Their central role in the control of a number of physiological mechanisms makes them an important area of both basic and applied biomedical research. This review presents an overview of basic and applied biology, and introduces the term cytokine technology to denote the use of cytokines as research tools for understanding the cellular and molecular regulation of hematopoiesis. A number of frontier technologies are reviewed, including fusion toxins, fusion proteins, and animal models of cytokine expression and regulation.</description><subject>Animals</subject><subject>Biological and medical sciences</subject><subject>Blood. Blood coagulation. Reticuloendothelial system</subject><subject>Cytokines - analysis</subject><subject>Cytokines - physiology</subject><subject>Cytokines - therapeutic use</subject><subject>Hematopoiesis</subject><subject>Humans</subject><subject>Medical sciences</subject><subject>Pharmacology. 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Blood coagulation. Reticuloendothelial system</topic><topic>Cytokines - analysis</topic><topic>Cytokines - physiology</topic><topic>Cytokines - therapeutic use</topic><topic>Hematopoiesis</topic><topic>Humans</topic><topic>Medical sciences</topic><topic>Pharmacology. 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| fulltext | fulltext |
| identifier | ISSN: 0192-6233 |
| ispartof | Toxicologic pathology, 1993-01, Vol.21 (2), p.251-257 |
| issn | 0192-6233 1533-1601 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_762269296 |
| source | MEDLINE; SAGE Complete A-Z List; Alma/SFX Local Collection |
| subjects | Animals Biological and medical sciences Blood. Blood coagulation. Reticuloendothelial system Cytokines - analysis Cytokines - physiology Cytokines - therapeutic use Hematopoiesis Humans Medical sciences Pharmacology. Drug treatments Receptors, Cytokine - metabolism Recombinant Proteins |
| title | Cytokine Technology in Basic and Applied Research on the Hematopoietic System |
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