Impact of obstructive interval and sperm granuloma on patency and pregnancy after vasectomy reversal
The objective of this study was to determine the effect of the obstructive interval and the presence of a sperm granuloma on vas patency and pregnancy rate following vasectomy reversal. We identified 334 patients with complete follow-up who met the inclusion criteria. There were significant associat...
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| Veröffentlicht in: | International journal of andrology 2010-10, Vol.33 (5), p.730-735 |
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| container_title | International journal of andrology |
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| creator | Magheli, A Rais-Bahrami, S Kempkensteffen, C Weiske, W.H Miller, K Hinz, S |
| description | The objective of this study was to determine the effect of the obstructive interval and the presence of a sperm granuloma on vas patency and pregnancy rate following vasectomy reversal. We identified 334 patients with complete follow-up who met the inclusion criteria. There were significant associations between the obstructive interval and procedure performed as well as with patient age. Patients with longer obstructive intervals were more often older (p < 0.001) and more likely to have a vaseoepididymostomy performed (p < 0.001). There was no association between the presence of a sperm granuloma or the length of the obstructive interval with post-operative vas patency and pregnancy rates. The only independent predictor of post-operative fertility was age of the female partner (p = 0.015). Our data clearly demonstrates that when state of the art surgical techniques are used, neither the presence of a sperm granuloma nor the obstructive interval serve as prognosticators of post-operative vas patency and pregnancy rates. However, when counselling patients and their female partners, it is of utmost importance to stress that the age of the female partner is an independent predictor of successful vasectomy reversal. |
| doi_str_mv | 10.1111/j.1365-2605.2009.01007.x |
| format | Article |
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We identified 334 patients with complete follow-up who met the inclusion criteria. There were significant associations between the obstructive interval and procedure performed as well as with patient age. Patients with longer obstructive intervals were more often older (p < 0.001) and more likely to have a vaseoepididymostomy performed (p < 0.001). There was no association between the presence of a sperm granuloma or the length of the obstructive interval with post-operative vas patency and pregnancy rates. The only independent predictor of post-operative fertility was age of the female partner (p = 0.015). Our data clearly demonstrates that when state of the art surgical techniques are used, neither the presence of a sperm granuloma nor the obstructive interval serve as prognosticators of post-operative vas patency and pregnancy rates. However, when counselling patients and their female partners, it is of utmost importance to stress that the age of the female partner is an independent predictor of successful vasectomy reversal.</description><identifier>ISSN: 0105-6263</identifier><identifier>EISSN: 1365-2605</identifier><identifier>DOI: 10.1111/j.1365-2605.2009.01007.x</identifier><identifier>PMID: 19906186</identifier><identifier>CODEN: IJANDP</identifier><language>eng</language><publisher>Oxford, UK: Oxford, UK : Blackwell Publishing Ltd</publisher><subject>Adult ; Age Factors ; Aged ; Biological and medical sciences ; Female ; Fundamental and applied biological sciences. Psychology ; Granuloma - pathology ; Gynecology. Andrology. Obstetrics ; Humans ; Male ; Male genital diseases ; Mammalian male genital system ; Medical sciences ; Middle Aged ; obstructive interval ; Pregnancy ; Pregnancy Rate ; sperm granuloma ; Spermatozoa - pathology ; Time Factors ; Treatment Outcome ; Vas Deferens - surgery ; vasectomy ; vasectomy reversal ; Vasovasostomy - methods ; Vertebrates: reproduction</subject><ispartof>International journal of andrology, 2010-10, Vol.33 (5), p.730-735</ispartof><rights>2009 The Authors. 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We identified 334 patients with complete follow-up who met the inclusion criteria. There were significant associations between the obstructive interval and procedure performed as well as with patient age. Patients with longer obstructive intervals were more often older (p < 0.001) and more likely to have a vaseoepididymostomy performed (p < 0.001). There was no association between the presence of a sperm granuloma or the length of the obstructive interval with post-operative vas patency and pregnancy rates. The only independent predictor of post-operative fertility was age of the female partner (p = 0.015). Our data clearly demonstrates that when state of the art surgical techniques are used, neither the presence of a sperm granuloma nor the obstructive interval serve as prognosticators of post-operative vas patency and pregnancy rates. However, when counselling patients and their female partners, it is of utmost importance to stress that the age of the female partner is an independent predictor of successful vasectomy reversal.</description><subject>Adult</subject><subject>Age Factors</subject><subject>Aged</subject><subject>Biological and medical sciences</subject><subject>Female</subject><subject>Fundamental and applied biological sciences. Psychology</subject><subject>Granuloma - pathology</subject><subject>Gynecology. Andrology. Obstetrics</subject><subject>Humans</subject><subject>Male</subject><subject>Male genital diseases</subject><subject>Mammalian male genital system</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>obstructive interval</subject><subject>Pregnancy</subject><subject>Pregnancy Rate</subject><subject>sperm granuloma</subject><subject>Spermatozoa - pathology</subject><subject>Time Factors</subject><subject>Treatment Outcome</subject><subject>Vas Deferens - surgery</subject><subject>vasectomy</subject><subject>vasectomy reversal</subject><subject>Vasovasostomy - methods</subject><subject>Vertebrates: reproduction</subject><issn>0105-6263</issn><issn>1365-2605</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2010</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqNkUuP0zAUhS0EYsrAXwBvEKsEP-JHNkijEQyFakCCYSQ21o3rVCl5jZ2U9t_jNFVZgjd-3O8cX52LEKYkpXG93aaUS5EwSUTKCMlTQglR6f4RWpwLj9EivopEMskv0LMQtoQQrjl9ii5onhNJtVyg9bLpwQ64K3FXhMGPdqh2Dlft4PwOagztGofe-QZvPLRj3TWAuxb3MLjWHo7l3rtNC8dbGVV4B8HZoWsO2Lud8wHq5-hJCXVwL077Jbr78P779cdk9eVmeX21SqzIuEoKm1uVidxqrnghZVFo4cCxUspccC6E5sIqUoIuGRWCZFpZlhdEWwqFcBm_RG9m3953D6MLg2mqYF1dQ-u6MRglGZNSU_JvUvA811TISOqZtL4LwbvS9L5qwB8MJWYahtmaKXMzZW6mYZjjMMw-Sl-ePhmLxq3_Ck_pR-D1CYBgoS5jwrYKZ45xRlRGJu7dzP2uanf47wbM8tPV7XSMBslsUIXB7c8G4H8ZqbgS5v72xqz4zx9f9b02nyP_auZL6AxsfGzq7hsjlBOqdcal5H8A67C93g</recordid><startdate>201010</startdate><enddate>201010</enddate><creator>Magheli, A</creator><creator>Rais-Bahrami, S</creator><creator>Kempkensteffen, C</creator><creator>Weiske, W.H</creator><creator>Miller, K</creator><creator>Hinz, S</creator><general>Oxford, UK : Blackwell Publishing Ltd</general><general>Blackwell Publishing Ltd</general><general>Blackwell</general><scope>FBQ</scope><scope>BSCLL</scope><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>7T5</scope><scope>H94</scope></search><sort><creationdate>201010</creationdate><title>Impact of obstructive interval and sperm granuloma on patency and pregnancy after vasectomy reversal</title><author>Magheli, A ; Rais-Bahrami, S ; Kempkensteffen, C ; Weiske, W.H ; Miller, K ; Hinz, S</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c5437-bc9c7459c8373b66bb85eae2f66953355835c70fa8f21550487c29b08c1ab5e43</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2010</creationdate><topic>Adult</topic><topic>Age Factors</topic><topic>Aged</topic><topic>Biological and medical sciences</topic><topic>Female</topic><topic>Fundamental and applied biological sciences. Psychology</topic><topic>Granuloma - pathology</topic><topic>Gynecology. Andrology. Obstetrics</topic><topic>Humans</topic><topic>Male</topic><topic>Male genital diseases</topic><topic>Mammalian male genital system</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>obstructive interval</topic><topic>Pregnancy</topic><topic>Pregnancy Rate</topic><topic>sperm granuloma</topic><topic>Spermatozoa - pathology</topic><topic>Time Factors</topic><topic>Treatment Outcome</topic><topic>Vas Deferens - surgery</topic><topic>vasectomy</topic><topic>vasectomy reversal</topic><topic>Vasovasostomy - methods</topic><topic>Vertebrates: reproduction</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Magheli, A</creatorcontrib><creatorcontrib>Rais-Bahrami, S</creatorcontrib><creatorcontrib>Kempkensteffen, C</creatorcontrib><creatorcontrib>Weiske, W.H</creatorcontrib><creatorcontrib>Miller, K</creatorcontrib><creatorcontrib>Hinz, S</creatorcontrib><collection>AGRIS</collection><collection>Istex</collection><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>Immunology Abstracts</collection><collection>AIDS and Cancer Research Abstracts</collection><jtitle>International journal of andrology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Magheli, A</au><au>Rais-Bahrami, S</au><au>Kempkensteffen, C</au><au>Weiske, W.H</au><au>Miller, K</au><au>Hinz, S</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Impact of obstructive interval and sperm granuloma on patency and pregnancy after vasectomy reversal</atitle><jtitle>International journal of andrology</jtitle><addtitle>Int J Androl</addtitle><date>2010-10</date><risdate>2010</risdate><volume>33</volume><issue>5</issue><spage>730</spage><epage>735</epage><pages>730-735</pages><issn>0105-6263</issn><eissn>1365-2605</eissn><coden>IJANDP</coden><abstract>The objective of this study was to determine the effect of the obstructive interval and the presence of a sperm granuloma on vas patency and pregnancy rate following vasectomy reversal. We identified 334 patients with complete follow-up who met the inclusion criteria. There were significant associations between the obstructive interval and procedure performed as well as with patient age. Patients with longer obstructive intervals were more often older (p < 0.001) and more likely to have a vaseoepididymostomy performed (p < 0.001). There was no association between the presence of a sperm granuloma or the length of the obstructive interval with post-operative vas patency and pregnancy rates. The only independent predictor of post-operative fertility was age of the female partner (p = 0.015). Our data clearly demonstrates that when state of the art surgical techniques are used, neither the presence of a sperm granuloma nor the obstructive interval serve as prognosticators of post-operative vas patency and pregnancy rates. 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| subjects | Adult Age Factors Aged Biological and medical sciences Female Fundamental and applied biological sciences. Psychology Granuloma - pathology Gynecology. Andrology. Obstetrics Humans Male Male genital diseases Mammalian male genital system Medical sciences Middle Aged obstructive interval Pregnancy Pregnancy Rate sperm granuloma Spermatozoa - pathology Time Factors Treatment Outcome Vas Deferens - surgery vasectomy vasectomy reversal Vasovasostomy - methods Vertebrates: reproduction |
| title | Impact of obstructive interval and sperm granuloma on patency and pregnancy after vasectomy reversal |
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