Using an improved Tol2 transposon system to produce transgenic zebrafish with epinecidin-1 which enhanced resistance to bacterial infection

In order to advance the application of antimicrobial peptides in aquaculture, transgenic zebrafish expressing the antimicrobial peptide, epinecidin-1, were developed and are reported on here. First, we cloned the zebrafish mylz2 promoter for this purpose. To characterize the activity of the mylz2 pr...

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Veröffentlicht in:	Fish & shellfish immunology 2010-05, Vol.28 (5), p.905-917
Hauptverfasser:	Peng, Kuan-Chieh, Pan, Chieh-Yu, Chou, Hong-Nong, Chen, Jyh-Yih
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Animals, Genetically Modified Antimicrobial Cationic Peptides - genetics Antimicrobial Cationic Peptides - immunology Danio rerio DNA Transposable Elements - genetics Epinecidin-1 Fish Diseases - immunology Fish Proteins - genetics Fish Proteins - immunology Freshwater Immune response Promoter Regions, Genetic - genetics Streptococcal Infections - immunology Streptococcal Infections - veterinary Streptococcus agalactiae Streptococcus agalactiae - physiology Tol2 transposon Transgenes - genetics Vibrio Infections - immunology Vibrio Infections - veterinary Vibrio vulnificus Vibrio vulnificus - physiology Zebrafish Zebrafish - genetics
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