Myocardial injury following endogenous catecholamine release in rabbits

Catecholamines (CAT) given in large doses produce cardiomyopathic changes in several animal species. This study was designed to determine if endogenous release can also induce cardiac injury. Rabbits were infused with doses of tyramine (TYR), ranging from 200 to 500 μg/min/kg, i.v. for 90 min. Arter...

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Veröffentlicht in:	Journal of molecular and cellular cardiology 1985-04, Vol.17 (4), p.377-387
Hauptverfasser:	Downing, S. Evans, Chen, Victor
Format:	Artikel
Sprache:	eng
Schlagworte:	Alloxan diabetes Animals Biological and medical sciences Cardiac muscle necrosis Cardiology. Vascular system Cardiomyopathies - etiology Cardiomyopathies - physiopathology Cardiomyopathy Catecholamines Catecholamines - blood Catecholamines - metabolism Coronary heart disease Diabetes Mellitus, Experimental - complications Female Heart Hemodynamics - drug effects Insulin - pharmacology Insulin, Cardiac O 2 demand Male Medical sciences Phentolamine Practolol Rabbits Receptors, Adrenergic, alpha - drug effects Sympatholytics - pharmacology Tyramine Tyramine - pharmacology
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