Effects of endothelium-derived nitric oxide on renal hemodynamics and function in the sheep fetus

We investigated the effects of the endothelium-derived nitric oxide system on renal hemodynamics and function during the 3rd trimester in a chronically catheterized fetal sheep preparation. Acetylcholine caused a significant decrease in renal vascular resistance (60% of the baseline value) as compar...

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Veröffentlicht in:	Pediatric research 1993-12, Vol.34 (6), p.755-761
Hauptverfasser:	BOGAERT, G. A, KOGAN, B. A, MEVORACH, R. A
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Arginine - analogs & derivatives Arginine - pharmacology Biological and medical sciences Blood Pressure - drug effects Blood Pressure - physiology Diuresis - drug effects Diuresis - physiology Embryology: invertebrates and vertebrates. Teratology Endothelium, Vascular - physiology Female Fetus - drug effects Fetus - physiology Fundamental and applied biological sciences. Psychology Glomerular Filtration Rate - drug effects Glomerular Filtration Rate - physiology Kidney - drug effects Kidney - physiology Natriuresis - drug effects Natriuresis - physiology Nitric Oxide - antagonists & inhibitors Nitric Oxide - physiology Nitroarginine Nitroprusside - pharmacology Organogenesis. Fetal development Organogenesis. Physiological fonctions Pregnancy Renal Circulation - drug effects Renal Circulation - physiology Sheep Vascular Resistance - drug effects Vascular Resistance - physiology Vasodilation - drug effects Vasodilation - physiology
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