Angiofollicular lymph node hyperplasia (Castleman's disease) associated with vertebral destruction

A 45‐year‐old man presented with lower thoracic pain, proteinuria, and destruction of thoracic vertebra from an adjacent unresectable paraspinal mass which, on biopsy, demonstrated angiofollicular lymph node hyperplasia (AFLNH). The patient received 3939 rad in 22 fractions to the mass and associate...

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Veröffentlicht in:Cancer 1985-08, Vol.56 (4), p.876-879
Hauptverfasser: Stokes, Steven H., Griffith, Rogers C., Thomas, Patrick R. M.
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container_title Cancer
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creator Stokes, Steven H.
Griffith, Rogers C.
Thomas, Patrick R. M.
description A 45‐year‐old man presented with lower thoracic pain, proteinuria, and destruction of thoracic vertebra from an adjacent unresectable paraspinal mass which, on biopsy, demonstrated angiofollicular lymph node hyperplasia (AFLNH). The patient received 3939 rad in 22 fractions to the mass and associated area of vertebral destruction. The patient is currently asymptomatic without recurrence of pain or progression of neurologic symptoms 5 years after radiotherapy. There has been resolution of the previous proteinuria. Serial computerized tomography scans and x‐rays show no change in the paraspinal mass nor resolution of the vertebral destruction adjacent to the mass. A search of the English literature has failed to identify any previous association of AFLNH and bone destruction.
doi_str_mv 10.1002/1097-0142(19850815)56:4<876::AID-CNCR2820560429>3.0.CO;2-C
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Hematologic involvement in other diseases</topic><topic>Other techniques and industries</topic><topic>Radiography, Thoracic</topic><topic>Thoracic Vertebrae - diagnostic imaging</topic><topic>Tomography, X-Ray Computed</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Stokes, Steven H.</creatorcontrib><creatorcontrib>Griffith, Rogers C.</creatorcontrib><creatorcontrib>Thomas, Patrick R. M.</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Cancer</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Stokes, Steven H.</au><au>Griffith, Rogers C.</au><au>Thomas, Patrick R. M.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Angiofollicular lymph node hyperplasia (Castleman's disease) associated with vertebral destruction</atitle><jtitle>Cancer</jtitle><addtitle>Cancer</addtitle><date>1985-08-15</date><risdate>1985</risdate><volume>56</volume><issue>4</issue><spage>876</spage><epage>879</epage><pages>876-879</pages><issn>0008-543X</issn><eissn>1097-0142</eissn><coden>CANCAR</coden><abstract>A 45‐year‐old man presented with lower thoracic pain, proteinuria, and destruction of thoracic vertebra from an adjacent unresectable paraspinal mass which, on biopsy, demonstrated angiofollicular lymph node hyperplasia (AFLNH). The patient received 3939 rad in 22 fractions to the mass and associated area of vertebral destruction. The patient is currently asymptomatic without recurrence of pain or progression of neurologic symptoms 5 years after radiotherapy. There has been resolution of the previous proteinuria. 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subjects Applied sciences
Biological and medical sciences
Exact sciences and technology
Hematologic and hematopoietic diseases
Humans
Hyperplasia - diagnostic imaging
Hyperplasia - radiotherapy
Lymph Nodes - pathology
Male
Medical sciences
Middle Aged
Other diseases. Hematologic involvement in other diseases
Other techniques and industries
Radiography, Thoracic
Thoracic Vertebrae - diagnostic imaging
Tomography, X-Ray Computed
title Angiofollicular lymph node hyperplasia (Castleman's disease) associated with vertebral destruction
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