Differential γ-interferon response of human colon carcinoma cells: inhibition of proliferation and modulation of immunogenicity as independent effects of γ-interferon on tumor cell growth

The effect of recombinant gamma-interferon (IFN-gamma) on established human colon carcinoma cell lines as well as fresh tumor cells from colon carcinoma patients has been investigated with respect to growth inhibition, enhancement of HLA expression, and modulation of immunogenicity. A direct antipro...

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Veröffentlicht in:	Cancer research (Chicago, Ill.) Ill.), 1985-08, Vol.45 (8), p.3503-3509
Hauptverfasser:	PFIZENMAIER, K, BARTSCH, H, SCHEURICH, P, SELIGER, B, UCER, U, VEHMEYER, K, NAGEL, G. A
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenocarcinoma - immunology Adenocarcinoma - pathology Antineoplastic agents Biological and medical sciences Cell Division - drug effects Cell Line Colonic Neoplasms - immunology Colonic Neoplasms - pathology Cytotoxicity, Immunologic - drug effects General aspects Histocompatibility Antigens Class II - analysis HLA Antigens - analysis HLA-DR Antigens Humans Interferon-gamma - pharmacology Lymphocyte Culture Test, Mixed Medical sciences Pharmacology. Drug treatments
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