WASH, WHAMM and JMY: regulation of Arp2/3 complex and beyond

Arp2/3 complex mediates the nucleation of actin filaments in multiple subcellular processes, and is activated by nucleation-promoting factors (NPFs) from the Wiskott–Aldrich Syndrome family. In exciting new developments, this family has grown by three members: WASH, WHAMM and JMY, which extend the r...

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Veröffentlicht in:	Trends in cell biology 2010-11, Vol.20 (11), p.650-661
Hauptverfasser:	Rottner, Klemens, Hänisch, Jan, Campellone, Kenneth G
Format:	Artikel
Sprache:	eng
Schlagworte:	Actin-Related Protein 2-3 Complex - metabolism Animals Endosomes - metabolism Humans Microfilament Proteins - metabolism Microtubules - metabolism Nuclear Proteins - metabolism Pathology Protein Transport Trans-Activators - metabolism
Online-Zugang:	Volltext
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