Identification and Evaluation of Constitutively Active Thyroid Stimulating Hormone Receptor Mutations

Thyroid stimulating hormone receptor (TSHR) is a guanine nucleotide-binding protein-coupled seven-transmembrane-domain receptor that controls the differentiation, growth, and function of the thyroid gland through stimulation of adenylyl cyclase and phospholipase C pathways. Thyroid stimulating hormo...

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Veröffentlicht in:	Constitutive Activity in Receptors and Other Proteins, Part A Part A, 2010, Vol.484, p.375-395
Hauptverfasser:	Lado-Abeal, Joaquin, Quisenberry, Leah R., Castro-Piedras, Isabel
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological Assay - methods Cell Line Flow Cytometry Humans Mice Molecular biology Mutation Phosphorylation Proteins Receptors, Thyrotropin - genetics Receptors, Thyrotropin - metabolism
Online-Zugang:	Volltext
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