The effect of concentration on the antioxidant effectiveness of α-tocopherol in lipid peroxidation induced by superoxide free radicals

Egg yolk phosphatidylcholine liposomes were rapidly oxidized in the presence of chelated iron and a superoxide-generating system. α-Tocopherol incorporated in the bilayer was oxidized at the same time. No lipid or α-tocopherol oxidation occurred in liposomes composed of dimyristoyl phosphatidylcholi...

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Veröffentlicht in:	Archives of biochemistry and biophysics 1985-07, Vol.240 (1), p.117-120
Hauptverfasser:	Fukuzawa, Kenji, Takase, Satoru, Tsukatani, Hiroaki
Format:	Artikel
Sprache:	eng
Schlagworte:	Antioxidants Applied sciences Ascorbic Acid - pharmacology Exact sciences and technology Free Radicals Lipid Bilayers Lipid Peroxides - biosynthesis Liposomes - metabolism Models, Chemical Other techniques and industries Oxidation-Reduction - drug effects Phosphatidylcholines - metabolism Superoxides - pharmacology Vitamin E - pharmacology
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