Similarities between interleukin-2 receptor number and affinity on activated B and T lymphocytes

Interleukin-2 (IL-2) is a T-cell-derived polypeptide hormone of 133 amino acids which exerts its growth-promoting activity via a surface receptor 1 . Originally, IL-2 was believed to be a unique growth factor for activated T cells 2 ; more recent studies, however, have demonstrated that certain B-ce...

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Veröffentlicht in:Nature (London) 1985-06, Vol.315 (6021), p.669-672
Hauptverfasser: Lowenthal, John W, Zubler, Rudolf H, Nabholz, Markus, MacDonald, H. Robson
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Sprache:eng
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